Abstract

http://ssrn.com/abstract=1004650
 
 

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Economic Benefit of Tuberculosis Control


Ramanan Laxminarayan


Center for Disease Dynamics, Economics & Policy; Princeton University

Eili Y Klein


Center for Advanced Modeling in the Social, Behavioral, and Health Sciences, Department of Emergency Medicine

Christopher Dye


World Health Organization

Katherine Floyd


World Health Organization

Sarah Darley


Resources for the Future

Olusoji Adeyi


World Bank

August 1, 2007

World Bank Policy Research Working Paper No. 4295

Abstract:     
Tuberculosis is the most important infectious cause of adult deaths after HIV/AIDS in low- and middle-income countries. This paper evaluates the economic benefits of extending the World Health Organization's DOTS Strategy (a multi-component approach that includes directly observed treatment, short course chemotherapy and several other components) as proposed in the Global Plan to Stop TB, 2006-2015. The authors use a model-based approach that combines epidemiological projections of averted mortality and economic benefits measured using value of statistical life for the Sub-Saharan Africa region and the 22 high-burden, tuberculosis-endemic countries in the world. The analysis finds that the economic benefits between 2006 and 2015 of sustaining DOTS at current levels relative to having no DOTS coverage are significantly greater than the costs in the 22 high-burden, tuberculosis-endemic countries and the Africa region. The marginal benefits of implementing the Global Plan to Stop TB relative to a no-DOTS scenario exceed the marginal costs by a factor of 15 in the 22 high-burden endemic countries, a factor of 9 (95% CI, 8-9) in the Africa region, and a factor of 9 (95% CI, 9-10) in the nine high-burden African countries. Uncertainty analysis shows that benefit-cost ratios of the Global Plan strategy relative to sustained DOTS were unambiguously greater than one in all nine high-burden countries in Africa and in Afghanistan, Pakistan, and Russia. Although HIV curtails the effect of the tuberculosis programs by lowering the life expectancy of those receiving treatment, the benefits of the Global Plan are greatest in African countries with high levels of HIV.

Number of Pages in PDF File: 59

Keywords: Health Monitoring & Evaluation, Disease Control & Prevention, Population Policies, Health Systems Development & Reform, Poverty and Health

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Date posted: August 5, 2007  

Suggested Citation

Laxminarayan, Ramanan and Klein, Eili Y and Dye, Christopher and Floyd, Katherine and Darley, Sarah and Adeyi, Olusoji, Economic Benefit of Tuberculosis Control (August 1, 2007). World Bank Policy Research Working Paper Series, Vol. , pp. -, 2007. Available at SSRN: http://ssrn.com/abstract=1004650

Contact Information

Ramanan Laxminarayan (Contact Author)
Center for Disease Dynamics, Economics & Policy ( email )
1616 P Street, NW
Washington, DC 20036
United States
HOME PAGE: http://www.cddep.org
Princeton University ( email )
22 Chambers Street
Princeton, NJ 08544
United States

Eili Y Klein
Center for Advanced Modeling in the Social, Behavioral, and Health Sciences, Department of Emergency Medicine ( email )
5801 Smith Ave
Davis Building, Suite 3220
Baltimore, MD 21212
United States
Christopher Dye
World Health Organization ( email )
20 Avenue Appia
Geneva 27, CH-1211
Switzerland
Katherine Floyd
World Health Organization
20 Avenue Appia
Geneva 27, CH-1211
Switzerland
Sarah Darley
Resources for the Future
1616 P Street, NW
Washington, DC 20036
United States
Olusoji Adeyi
World Bank
1818 H Street, NW
Washington, DC 20433
United States
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