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http://ssrn.com/abstract=1080089
 
 

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Comparison between Product Characteristics and Decision Analysis Supporting Decision-Makers in Public Health-Related Choices: A Study Model Applied to Anti-HPV Vaccines


Giampiero Favato


Kingston University

Francesco Saverio Mennini


University of Rome II

Andrea Monorchio


University of Siena - Faculty of Political Science

Emilio Mortilla


University of California, Berkeley

January 1, 2008


Abstract:     
Vaccines for the prevention of pathologies caused by Human Papillomavirus (HPV) are undoubtedly considered among the most advanced forms of biotechnological innovation. At present, two different vaccines are available: the bivalent vaccine, targeting the HPV-16 and 18 strains, and the quadrivalent vaccine, which targets the HPV-6, 11, 16 and 18 strains.

Observing the impact projections analysis, obtainable on the basis of data published in various studies, it is clear that a reduction of 10.0 euros, resulting from the ex-factory price differential of the two vaccines (in favour of the bivalent) hardly compensate for the considerable increase of the expenditure related to the failure to prevent HPV-induced outcomes, such as abnormal Pap-tests, colposcopies, low and high-grade precancerous lesions, in situ carcinomas, cervical carcinomas, vulvar dysplastic lesions, vaginal dysplastic lesions and genital warts.

A mere difference in ex-factory price should not be the only determinant of the vaccine's choice, in the light of the incremental prevention against cervical carcinoma caused by HPV-18 and vulvar carcinoma, and the avoidable risk of onset of genital warts.

Number of Pages in PDF File: 9

Keywords: spc, decision,analysis,HPV,vaccines,cost

JEL Classification: I11,I18

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Date posted: January 3, 2008  

Suggested Citation

Favato, Giampiero and Mennini, Francesco Saverio and Monorchio, Andrea and Mortilla, Emilio, Comparison between Product Characteristics and Decision Analysis Supporting Decision-Makers in Public Health-Related Choices: A Study Model Applied to Anti-HPV Vaccines (January 1, 2008). Available at SSRN: http://ssrn.com/abstract=1080089 or http://dx.doi.org/10.2139/ssrn.1080089

Contact Information

Giampiero Favato (Contact Author)
Kingston University ( email )
Kingston Hill
Kingston upon Thames
Surrey KT2 7LB
United Kingdom
Francesco Saverio Mennini
University of Rome II ( email )
Via di Tor Vergata
Rome, 00133
Italy
Andrea Monorchio
University of Siena - Faculty of Political Science ( email )
Siena
Italy
Emilio Mortilla
University of California, Berkeley ( email )
310 Barrows Hall
Berkeley, CA 94720
United States
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