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Market-Based Licensing for HPV Vaccines in Developing Countries


Kevin Outterson


Boston University School of Law

Aaron S. Kesselheim


Brigham and Women's Hospital/Harvard Medical School; Harvard University - Edmond J. Safra Center for Ethics

January 1, 2008

Health Affairs, Vol. 27, No. 1, 2008

Abstract:     
Human papillomavirus (HPV) vaccines hold great promise for preventing cervical cancer, but 93 percent of mortality worldwide occurs in low- and middle-income countries, where high vaccine costs can restrict dissemination. Current models for promoting international access to health care innovations include differential pricing, advance market commitments, and voluntary and compulsory licensing. Some of these mechanisms have been effective, but much room for improvement remains. We discuss the usefulness of a new type of license that uses market forces to lower prices through generic competition in low- and middle-income countries while ensuring that pharmaceutical companies are appropriately reimbursed for their research and development.

Number of Pages in PDF File: 14

Keywords: Compulsory license, HPV vaccine, generic open license, access to vaccines

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Date posted: November 22, 2009 ; Last revised: April 16, 2013

Suggested Citation

Outterson, Kevin and Kesselheim, Aaron S., Market-Based Licensing for HPV Vaccines in Developing Countries (January 1, 2008). Health Affairs, Vol. 27, No. 1, 2008. Available at SSRN: http://ssrn.com/abstract=1510885

Contact Information

Kevin Outterson (Contact Author)
Boston University School of Law ( email )
765 Commonwealth Avenue
Boston, MA 02215
United States
Aaron S. Kesselheim
Brigham and Women's Hospital/Harvard Medical School ( email )
1620 Tremont St
Suite 3030
Boston, MA 02120
United States
617-278-0930 (Phone)
617-232-8602 (Fax)
Harvard University - Edmond J. Safra Center for Ethics ( email )
124 Mount Auburn Street
Suite 520N
Cambridge, MA 02138
United States

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