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Genes, Economics, and HappinessJan-Emmanuel De NeveUniversity College London; London School of Economics & Political Science (LSE) Nicholas A. ChristakisHarvard Medical School - Department of Health Care Policy James H. FowlerUC San Diego Division of Social Sciences; UC San Diego School of Medicine Bruno S. FreyCREMA; Behavioural Science; Economics August 2012 CESifo Working Paper Series No. 2946 Abstract: We explore the influence of genetic variation on subjective well-being by employing a twin design and genetic association study. In a nationally-representative twin sample, we first show that about 33% of the variation in life satisfaction is explained by genetic variation. Although previous studies have shown that baseline happiness is significantly heritable, little research has considered molecular genetic associations with subjective well-being. We study the relationship between a functional polymorphism on the serotonin transporter gene (5-HTTLPR) and life satisfaction. We initially find that individuals with the longer, transcriptionally more efficient variant of this genotype report greater life satisfaction (n=2,545, p=0.012). However, our replication attempts on independent samples produce mixed results indicating that more work needs to be done to better understand the relationship between this genotype and subjective well-being. This work has implications for how economists think about the determinants of utility, and the extent to which exogenous shocks might affect individual well-being.
Number of Pages in PDF File: 51 Keywords: happiness, subjective well-being, genetics JEL Classification: A12, D03, D87, Z00 working papers seriesDate posted: February 18, 2010Suggested CitationContact Information
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