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Transarterial Chemoembolization Plus Stent Placement for Treatment of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: A Meta-Analysis
14 Pages Posted: 23 Jun 2019
More...Abstract
Purpose To assess the safe and efficiency of TACE+Stent for treatment of HCC with PVTT.
Materials and Methods: We searched to Cochrane library, PubMed, EMBASE, CNKI, Wangfang Data and CQVIP. We assessed the qualities of included studies. We analyzed the characteristic data, tested heterogeneity, explored heterogeneity and tested publication bias by software-Review Manger 3.5.
Results: Totally 8 clinical controlled trials were selected with the inclusion criterion. The results shown that the pressure of main portal vein after stent placement were significant lower than no stent placement. The cumulative stent patency rates and survival rates in 6 and 12 month of TACE+Stent were lower than TACE+Stent+I125 seed/3-DCRT. The survival rates in 6 and 12 moth of TACE+Stent was higher than TACE alone.
Conclusion: For HCC patients with PVTT, TACE+stent was safe and efficient. The efficiency of TACE+stent were better than TACE alone. TACE+stent combined with I125 seed/3-DCRT was more effective than TACE+stent.
Funding: No funding support.
Declaration of Interest: The authors made no disclosures.
Ethics Approval Statement: Not required.
Keywords: Hepatocellular carcinoma; Transarterial chemoembolization; Portal vein tumor thrombus; Stent; Meta-analysis
Suggested Citation: Suggested Citation