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Deep Learning and Behavioral Theory: An Improved Analytic Method to Understand HPV Vaccination Intentions from Twitter Discussion

37 Pages Posted: 3 Oct 2019

See all articles by Jingcheng Du

Jingcheng Du

University of Texas at Houston - School of Biomedical Informatics

Chongliang Luo

University of Pennsylvania - Perelman School of Medicine

Ross Shegog

University of Texas at Houston - School of Public Health

Jiang Bian

University of Florida

Yong Chen

University of Pennsylvania - Perelman School of Medicine

Cui Tao

University of Texas at Houston - School of Biomedical Informatics

More...

Abstract

Background: HPV vaccine refusal or hesitancy is common among parents of adolescents, which poses a public health threat to communities. An understanding of public perception of the HPV vaccine from the perspective of behavior change theories (e.g., Health Belief Model [HBM], Theory of Planned Behavior [TPB]) can facilitate effective and targeted vaccine promotion strategies. In this regard, social media is considered a major and credible source to access public perception.

Methods: We performed an evaluation of various machine learning and deep learning algorithms in mapping HPV vaccine-related Twitter discussions to major theoretical constructs of HBM and TPB. Deep learning models were then applied to map the sampled Twitter discussions (collected from January 2014 to October 2018) to the theoretical constructs. Locally estimated scatterplot smoothing (LOESS) was then adopted to reveal trends of constructs.

Findings: Deep-learning algorithms achieved better performance compared with machine-learning algorithms on mapping Twitter discussion to the constructs of behavior change theories. The use of pre-trained word embedding can further improve the performance of deep-learning models. LOESS has revealed trends of constructs: for example, in the recent two years Positive attitude toward the HPV vaccine shows an increasing trend, while Negative attitude shows a decreasing trend.

Interpretation: The retrospective analysis of theoretical constructs toward HPV vaccine provides a better understanding of public perception and its evolving trends in terms of multiple dimensions. The increasing prevalence in Positive attitude toward the HPV vaccine benefits from the significant efforts of public health professionals on HPV vaccine promotion; the increase in Perceived severity could result from the promotion strategy that the HPV vaccine has been more associated with cancer prevention than with genital warts.

Funding Statement: Cancer Prevention and Research Institute of Texas, National Institutes of Health, National Science Foundation.

Declaration of Interests: JD received funding from the UTHealth Innovation for Cancer Prevention Research Training Program Predoctoral Fellowship (Cancer Prevention and Research Institute of Texas Grant No. RP160015); JB received funding from the National Science Foundation under Award Number No. 1734134; RS received funding from the CPRIT Dissemination Grant PP190041. CT and YC received funding from the National Institutes of Health under Award Nos. R01LM011829 and R01AI130460.

Ethical Approval Statement: Not required.

Keywords: HPV vaccine, deep learning, Twitter, machine learning, behavioral theory

Suggested Citation

Du, Jingcheng and Luo, Chongliang and Shegog, Ross and Bian, Jiang and Chen, Yong and Tao, Cui, Deep Learning and Behavioral Theory: An Improved Analytic Method to Understand HPV Vaccination Intentions from Twitter Discussion (September 27, 2019). Available at SSRN: https://ssrn.com/abstract=3460688 or http://dx.doi.org/10.2139/ssrn.3460688

Jingcheng Du

University of Texas at Houston - School of Biomedical Informatics

7000 Fannin
Suite 600
Houston, TX 77030
United States

Chongliang Luo

University of Pennsylvania - Perelman School of Medicine

423 Guardian Drive
Philadelphia, PA 19104
United States

Ross Shegog

University of Texas at Houston - School of Public Health

1200 Pressler Street
Houston, TX 77030
United States

Jiang Bian

University of Florida

PO Box 117165, 201 Stuzin Hall
Gainesville, FL 32610-0496
United States

Yong Chen

University of Pennsylvania - Perelman School of Medicine

423 Guardian Drive
Philadelphia, PA 19104
United States

Cui Tao (Contact Author)

University of Texas at Houston - School of Biomedical Informatics ( email )

7000 Fannin
Suite 600
Houston, TX 77030
United States

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