Download This Paper
Preprints with The Lancet is a collaboration between The Lancet Group of journals and SSRN to facilitate the open sharing of preprints for early engagement, community comment, and collaboration. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early-stage research papers that have not been peer-reviewed. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. The findings should not be used for clinical or public health decision-making or presented without highlighting these facts. For more information, please see the FAQs.
Global Pattern and Determinants of COVID-19 Vaccine Coverage and Progression: A Global Ecological Study
29 Pages Posted: 1 Mar 2022
More...Abstract
Background: Understanding and minimizing existing global COVID-19 vaccination disparities is critical to global population health and eliminating health inequities. The study aims to investigate the disparities of vaccination coverage and progression and the associated economic and educational determinants to inform global COVID-19 vaccination strategies.
Methods: Study data of COVID-19 vaccination from 206 countries were derived from “our world in data” website. Correlation and multiple linear regression analysis were used to examine the effects of GDP, Gini index, education, and their interactions on the coverage and progression of the COVID-19 vaccinations.
Findings: The coverage of COVID-19 vaccination ranged from less than 30 doses to more than 200 doses for total number of doses, from less than 15% to more than 75% for proportion of people vaccinated, from less than 15% to more than 60% for proportion of people fully vaccinated. Similarly, the progression of vaccination ranged from less than 0.1 to more than 0.8 for progression of total number of doses, from less than 0.1 to more than 0.5 for progression of proportion of people vaccinated, and from less than 0.1 to more than 0.5 for progression of proportion of people fully vaccinated. GDP and education were positively associated with the coverage and progression, while Gini index was negatively associated with the coverage and progression. Negative interaction between GDP per capita and education was also observed for coverage (β=-0.01, p<0.001) and progression (β=-0.01, p<0.001).
Interpretation: Substantial geographic disparities existed for the coverage and progression of COVID-19 vaccination. Economy and education are two important factors contributing to the disparities. Different countries may adopt varied strategies to promote the national distribution and vaccination of COVID-19 vaccines.
Funding Information: This work was supported by the starting funding package from Wuhan University (PI: Bin Yu). The sponsors had no role in the design and conduct of this study.
Declaration of Interests: We have read and understood the publication policy on the declaration of interests and declare that we have no competing interests.
Ethics Approval Statement: The study was secondary data analysis. No personal interests are involved. Data analysis was designed and performed according to ethical standards of the responsible committee on human studies and the Helsinki Declaration (1975, revised in 1983) and has been approved by the University Health System Institutional Review Board (IRB).
Keywords: COVID-19 vaccination, GDP per capita, Gini index, education
Suggested Citation: Suggested Citation