Download This PaperCoronavirus 2: Analysis of Regularity of Complete Genome (SARS-CoV-2/Hu/DP/Kng/19-020 RNA)
6 Pages Posted: 14 Apr 2020 Last revised: 5 Jun 2020
Date Written: April 11, 2020
Abstract
This paper shows a technique for the detection of regularities in the complete genome of Coronavirus 2. For this, the concept of intervals in the RNA chain and their comparison within the known sequence is used. The Maximum Regularity Index was applied. The results show that areas of high regularity are identified that coincide with ORF10, Gene N, nucleocapsid phosphoprotein and others. The interval around 3500 and the interval around 11000, respectively, appear with high values of regularity and this do not correspond to particularly documented elements (both within Gene: Orf1ab). It might be in the interest of giving importance to that region. The detection of regularities can enhance the creation of biochemical or genetic techniques to deactivate certain functions of Coronavirus 2 or control its effects.
Note: Funding: The funds used were provided by the Universidad Nacional. The results are part of the research project SIA0130-10.
Conflict of Interest: No competing interests.
Keywords: Coronavirus 2, SARS-CoV-2, Complete Genome, RNA, index of maximum regularity, COVID-19, NCBI
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