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MedRN: Translational Oncology (Topic)

393 Total downloads

Viewing: 1 - 19 of 19 papers

1.

Generalizing Research Findings for Enhanced Reproducibility: A Translational Medicine Case Study

Number of pages: 13 Posted: 12 Sep 2017 Last Revised: 28 Mar 2019
Working Paper Series
KPA Ltd. and Hebrew University of Jerusalem - Faculty of Medicine
Downloads 136
3.

DNA-Demethylating Agents Enhance Cytolytic Activity of CD8 T Cells and Anti-Tumor Immunity

Number of pages: 52 Posted: 04 Apr 2018
Working Paper Series
Princess Margaret Cancer Centre, Princess Margaret Cancer Centre, University of Sao Paulo (USP) - Instituto de Ciências Biomédicas, University of Montreal - Faculté de Pharmacie, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre, Vall d’Hebron Institute of Oncology (VHIO) - Preclinical Research Program, University of Montreal - Institut du Cancer de Montréal, F. Hoffmann-La Roche Ltd - Roche Innovation Center Zurich, University of Sao Paulo (USP) - Instituto de Ciências Biomédicas, Université de Rennes 1 - INSERM, Princess Margaret Cancer Centre, Vall d’Hebron Institute of Oncology (VHIO) - Preclinical Research Program, University of Montreal - Faculté de Pharmacie and Princess Margaret Cancer Centre
Downloads 48
4.

Targeting FROUNT with Disulfiram Regulates Macrophage Responses in Cancer

Number of pages: 48 Posted: 10 Apr 2018
Working Paper Series
University of Tokyo - Department of Molecular Preventive Medicine, University of Tokyo - Department of Molecular Preventive Medicine, Chiba Cancer Center - Department of Thoracic Disease, University of Tokyo - Department of Molecular Preventive Medicine, Kumamoto University - Department of Structural BioImaging, Chiba Cancer Center, University of Tokyo - Department of Molecular Preventive Medicine, Kumamoto University - Department of Cell Pathology, Chiba Cancer Center, University of Tokyo - Department of Molecular Preventive Medicine, University of Tokyo - Graduate School of Pharmaceutical Sciences, Kumamoto University - Department of Cell Pathology, Chiba Cancer Center, Chiba Cancer Center - Department of Thoracic Disease, University of Tokyo - Drug Discovery Initiative, University of Tokyo - Drug Discovery Initiative, University of Tokyo - Drug Discovery Initiative, Yeungnam University - College of Medicine, National Institutes for Quantum and Radiological Science and Technology - Department of Radiopharmaceuticals Development, University of Tokyo - Graduate School of Pharmaceutical Sciences, Chiba Cancer Center, Kumamoto University - Department of Structural BioImaging and University of Tokyo - Department of Molecular Preventive Medicine
Downloads 23
5.

The SINEB1 Element in the Long Non-Coding RNA Malat1 is Necessary for TDP-43 Proteostasis

Number of pages: 42 Posted: 13 Dec 2018
Working Paper Series
Baylor University - Graduate Program in Translational Biology and Molecular Medicine, Baylor University - Department of Molecular and Cellular Biology, Baylor University - Department of Neuroscience, University of Texas at Houston, UTHealth McGovern Medical School, Department of Biochemistry and Molecular Biology, University of Texas at Houston, UTHealth McGovern Medical School, Department of Biochemistry and Molecular Biology, University of Texas at Houston, UTHealth McGovern Medical School, Department of Biochemistry and Molecular Biology, Baylor University - Integrated Microscopy Core, Baylor University - Integrated Microscopy Core, Baylor University - Integrated Microscopy Core, Baylor University - Department of Pharmacology and Chemical Biology, Baylor University - Department of Pharmacology and Chemical Biology, Michael E. DeBakey High School for Health Professions, Baylor University - Department of Molecular and Cellular Biology, Baylor University - Department of Molecular and Cellular Biology, Baylor University - Graduate Program in Translational Biology and Molecular Medicine, Baylor University - Department of Pharmacology and Chemical Biology, Baylor University - Department of Pharmacology and Chemical Biology, Baylor University - Department of Molecular Physiology and Biophysics, Baylor University - Integrated Microscopy Core, Baylor University - Department of Molecular and Cellular Biology, University of Texas at Houston, UTHealth McGovern Medical School, Department of Biochemistry and Molecular Biology and Baylor University - Graduate Program in Translational Biology and Molecular Medicine
Downloads 23
6.

Translational and HIF1α-Dependent Metabolic Reprograming Underpin Oncometabolome Plasticity and Synergy Between Oncogenic Kinase Inhibitors and Biguanides

Number of pages: 64 Posted: 11 Apr 2018
Working Paper Series
McGill University - Lady Davis Institute for Medical Research, McGill University - Rosalind and Morris Goodman Cancer Research Centre, University of Texas at San Antonio - Department of Molecular Medicine and Barshop Institute for Longevity and Aging Studies, McGill University - Lady Davis Institute for Medical Research, McGill University - Lady Davis Institute for Medical Research, McGill University - Lady Davis Institute for Medical Research, McGill University - Lady Davis Institute for Medical Research, Karolinska Institutet - Science for Life Laboratory, University of Toronto - Department of Laboratory Medicine and Pathobiology, McGill University - McGill University Centre for Research in Neuroscience, McGill University - Lady Davis Institute for Medical Research, McGill University - Metabolomics Core Facility, McGill University - Metabolomics Core Facility, McGill University - Lady Davis Institute for Medical Research, McGill University - Rosalind and Morris Goodman Cancer Research Centre, McGill University - Lady Davis Institute for Medical Research and McGill University - Lady Davis Institute for Medical Research
Downloads 19
7.

Number of Microstates of Dark DNAs in Extra Dimensions for Normal and Cancerous Cells

Number of pages: 16 Posted: 31 May 2019
Working Paper Series
Research Institute for Astronomy and Astrophysics of Maragha (RIAM)
Downloads 9
8.

Exosomes Derived from HeLa Cells Break Down Vascular Integrity by Triggering Endoplasmic Reticulum Stress in Endothelial Cells

Number of pages: 49 Posted: 16 Apr 2019
Working Paper Series
Zhejiang University - Department of Cardiology, Zhejiang University - Department of Cardiology, Zhejiang University - Department of Cardiology, Zhejiang University - Department of Cardiology and Zhejiang University - Department of Cardiology
Downloads 8
9.

BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication

Number of pages: 30 Posted: 07 Jan 2019
Working Paper Series
University of Birmingham - Institute of Cancer and Genomic Sciences, University of Birmingham - Institute of Cancer and Genomic Sciences and University of Birmingham - Institute of Cancer and Genomic Sciences
Downloads 7
10.

Tumor Establishment Requires Tumor Autonomous and Non-Autonomous Decoupling of EGF Signaling from Apoptosis

Number of pages: 34 Posted: 06 Feb 2019
Working Paper Series
Stanford University - Department of Molecular and Cellular Physiology, Stanford University - Department of Molecular and Cellular Physiology and Stanford University - Department of Molecular and Cellular Physiology
Downloads 7
11.

ATG12 Deficiency Leads to Tumor Cell Oncosis Owing to Diminished Mitochondrial Biogenesis and Reduced Cellular Bioenergetics

Number of pages: 61 Posted: 29 Jan 2019
Working Paper Series
University of Bern - Institute of Pharmacology, University of Bern - Institute of Pharmacology, University of Bern - Institute of Pharmacology, University of Bern - Institute of Pharmacology, University of Bern - Institute of Pharmacology, University of Bern - Institute of Clinical Chemistry, University of Bern - Institute of Clinical Chemistry, University of Bern - Institute of Clinical Chemistry, University of Bern - Institute of Pharmacology, University of Ljubljana - Faculty of Pharmacy, University of Lausanne - Electron Microscopy Facility, University of Bern - Institute of Pathology, University of Bern - Institute of Clinical Chemistry, University of Bern - Institute of Pathology and University of Bern - Institute of Pharmacology
Downloads 6
12.

Novel Mitochondrion-Targeting Copper(II) Complex Induces HK2 Malfunction and Inhibits Glycolysis via Drp1 Mediating Mitophagy in HCC

Number of pages: 44 Posted: 12 Apr 2019
Working Paper Series
Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University - State Key Laboratory of Coordination Chemistry, Nanjing University - State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University - State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine (NJUCM) - Affiliated Hospital, Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica and Nanjing University of Chinese Medicine (NJUCM) - Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica
Downloads 5
13.

Population Change of Myeloid and Lymphoid Cells Contributes to the Blood-Based Protein Biomarkers

Number of pages: 56 Posted: 21 Dec 2018
Working Paper Series
Fujian Medical University, Fujian Medical University, Fujian Medical University, Fujian Medical University, Fujian Medical University, Fujian Medical University - Department of Bioinformatics, Fujian Medical University - Department of Reproductive Medicine Centre and Fujian Medical University - Department of Bioinformatics
Downloads 4
14.

Promoter Hypomethylation and Phosphorylation of Phosphoglycerate Kinase 1 Involved in Warburg Effect Are Associated with Poor Prognosis in Cancer

Number of pages: 44 Posted: 03 Jun 2019
Working Paper Series
Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - National Clinical Research Center for Cancer, Chinese Academy of Medical Sciences - National Clinical Research Center for Cancer, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Chinese Academy of Medical Sciences - Department of Thoracic Surgery, Zhejiang University - Zhejiang Provincial Key Laboratory of Pancreatic Disease and Chinese Academy of Medical Sciences - Department of Thoracic Surgery
Downloads 4
15.

Circ-0000284 Arouses Malignant Phenotype of Cholangiocarcinoma Cells and Regulates the Biological Functions of Peripheral Cells Through Cellular Communication

Number of pages: 39 Posted: 26 Apr 2019
Working Paper Series
Nanjing Medical University - State Key Laboratory of Reproductive Medicine, Nanjing Medical University - Department of Hepatobiliary and Pancreatic Surgery, Nanjing Medical University - Department of Hepatobiliary and Pancreatic Surgery, Nanjing Medical University - State Key Laboratory of Reproductive Medicine and Nanjing Medical University - Department of Hepatobiliary and Pancreatic Surgery
Downloads 3
16.

LncRNA HotairM1 Depletion Promotes Self-Renewal of Cancer Stem Cells Through HOXA1-Nanog Regulation Loop

Number of pages: 41 Posted: 04 Jun 2019
Working Paper Series
Shanghai Jiao Tong University (SJTU) - Department of Ophthalmology, Shanghai Jiao Tong University (SJTU) - Department of Ophthalmology, Tong Ji University and Shanghai Jiao Tong University (SJTU) - Department of Ophthalmology
Downloads 3
17.

Measuring the Economic and Academic Impact of Philanthropic Funding: The Breast Cancer Research Foundation

Number of pages: 26 Posted: 12 Jun 2019
Working Paper Series
affiliation not provided to SSRN, Memorial Sloan Kettering Cancer Center, Breast Cancer Research Foundation and Massachusetts Institute of Technology (MIT) - Sloan School of Management
Downloads 3
18.

Timing the Initiation of Multiple Myeloma

CANCER-CELL-D-19-00505
Number of pages: 122 Posted: 25 Jun 2019
Working Paper Series
Memorial Sloan Kettering Cancer Center - Myeloma Service, Memorial Sloan Kettering Cancer Center - Myeloma Service, University of Milan, Faculty of Medicine, Oncology and Hemato-Oncology Department, Wellcome Sanger Institute, Institut D’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Essex, Wellcome Sanger Institute, Wellcome Sanger Institute, Wellcome Sanger Institute, University of Milan, Faculty of Medicine, Oncology and Hemato-Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori - Division of Hematology and Bone Marrow Transplantation, University of Milan, Harvard University - Dana-Farber Cancer Institute, University of Nantes, Memorial Sloan Kettering Cancer Center - Myeloma Service, University of California, San Diego (UCSD) - Moores Cancer Center, University of Barcelona, Patologia Molecular de Neoplàsies Limfoides, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Ulm, IUC-Oncopole, Memorial Sloan Kettering Cancer Center - Myeloma Service, Harvard University - Dana-Farber Cancer Institute, Wellcome Genome Campus - Cancer Genome Project and Memorial Sloan Kettering Cancer Center - Myeloma Service
Downloads 2
19.

Tumor-Secreted GRP78 Facilitates the Migration of Macrophages into Tumors by Promoting Cytoskeleton Remodeling

Number of pages: 50 Posted: 06 Dec 2018
Working Paper Series
Shanxi University - Key Laboratory of Chemical Biology and Molecular Engineering, Shanxi University, Shanxi University - Key Laboratory of Chemical Biology and Molecular Engineering, Shanxi University, University of Minnesota - Minneapolis and Shanxi University - Key Laboratory of Chemical Biology and Molecular Engineering
Downloads 2