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Cell Chemical Biology : Papers Under Review

Viewing: 1 - 20 of 120 papers

1.

Matrix-Augmented Pooling Strategy for High-Throughput Target Deconvolution Reveals Cell Type Specific Off-Targets and Responses

Hongchao Ji
Southern University of Science and Technology - Department of Chemistry
Xue Lu
Southern University of Science and Technology - Department of Chemistry
Posted: 21 Nov 2022
Publication Status: Under Review
Downloads 5
2.

In vivo Bioluminescence Imaging of Labile Iron in Xenograft Models and Liver Using FeAl-1, an Iron-Activatable Form of D-Luciferin

Ryan L. Gonciarz
University of California, San Francisco (UCSF) - Department of Pharmaceutical Chemistry
Honglin Jiang
University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center
Posted: 18 Nov 2022
Publication Status: Under Review
Downloads 6
3.

Antiplasmodial Peptaibols Act Through Membrane Directed Mechanisms

Jennifer E. Collins
University of Central Florida - Division of Molecular Biology and Microbiology
Jin Woo Lee
University of Oklahoma - Department of Chemistry and Biochemistry
Posted: 09 Nov 2022
Publication Status: Under Review
Downloads 7
4.

Human Gut Actinobacteria Boost Drug Absorption by Secreting P-Glycoprotein ATPase Inhibitors

Than S. Kyaw
University of California, San Francisco (UCSF) - Department of Microbiology and Immunology
Moriah Sandy
University of California, San Francisco (UCSF) - Department of Microbiology and Immunology
Posted: 03 Nov 2022
Publication Status: Under Review
Downloads 4
5.

Screening of E3 Ligases Uncovers KLHDC2 as an Efficient Proximity-Induced Degrader of K-RAS, STK33, β-catenin and FoxP3

Sascha Röth
University of Dundee - MRC Protein Phosphorylation and Ubiquitylation Unit
Bill Carton
University of Dundee - MRC Protein Phosphorylation and Ubiquitylation Unit
Posted: 27 Sep 2022
Publication Status: Under Review
Downloads 44
6.

Gaussian Process Captures the Conversion of the Pathogenic Alpha-1-Antitrypsin Fold by ATF6 Enhanced Proteostasis

Shuhong Sun
The Scripps Research Institute - Department of Molecular Medicine
Chao Wang
The Scripps Research Institute - Department of Molecular Medicine
Posted: 26 Sep 2022
Publication Status: Review Complete
Downloads 7
7.

Single-Cell Sequencing Reveals Double-Kill Mechanism of Artemisinin Against Plasmodium

Jun Sun
Tongji University - Institute for Infectious Diseases and Vaccine Development
Fujiang Guo
Shanghai University of Traditional Chinese Medicine - School of Pharmacy
Posted: 16 Sep 2022
Publication Status: Review Complete
Downloads 9
8.

Utilizing Directed Evolution to Interrogate and Optimize CRISPR/Cas Guide RNA Scaffolds

Korie Bush
Duke University - Department of Surgery
Amy C. Yan
Duke University - Department of Surgery
Posted: 15 Sep 2022
Publication Status: Review Complete
Downloads 7
9.

AGC Kinase Inhibitors Regulate STING Signaling Through SGK-Dependent and SGK-Independent Mechanisms

Johnny Castillo Cabrera
University of North Carolina (UNC) at Chapel Hill - Department of Pathology and Laboratory Medicine
Hong Dang
University of North Carolina (UNC) at Chapel Hill - Department of Pathology and Laboratory Medicine
Posted: 15 Aug 2022
Publication Status: Under Review
Downloads 4
10.

Redox Proteomics Combined with Proximity Labeling Enables Monitoring of Localized Cysteine Oxidation in Cells

Eranthie Weerapana
Boston College - Department of Chemistry
Eleni A. Kisty
Boston College - Department of Chemistry
Posted: 23 Jun 2022
Publication Status: Under Review
Downloads 17
11.

Arginine 65 Methylation of Neurogenin 3 by PRMT1 Is Required for Pancreatic Endocrine Development of hESCs

Gahyang Cho
Korea Advanced Institute of Science and Technology (KAIST) - Department of Biological Sciences
Kwangbeom Hyun
Korea Advanced Institute of Science and Technology (KAIST) - Department of Biological Sciences
Posted: 21 Jun 2022
Publication Status: Review Complete
Downloads 6
12.

Targeted Degradation of STAT3 via Chaperone-Mediated Autophagy by nanoCMATAC Platform

Haohao Song
National Center for Nanoscience and Technology - CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety
Wenping Huang
National Center for Nanoscience and Technology - CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety
Posted: 21 Jun 2022
Publication Status: Review Complete
Downloads 7
13.

Modulation of Tau Tubulin Kinases ((TTBK1 and TTBK2) Impacts Ciliogenesis

Frances Potjewyd
University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium
Ariana B. Marquez
University of North Carolina (UNC) at Chapel Hill - Human Pluripotent Stem Cell Core
Posted: 19 May 2022
Publication Status: Review Complete
Downloads 3
14.

Identifying Reactive Sites on Diacylglycerol Kinases for Covalent Binding in Cells

Roberto Mendez
University of Virginia - Department of Chemistry
Minhaj S. Shaikh
University of Virginia - Department of Chemistry
Posted: 17 May 2022
Publication Status: Review Complete
Downloads 6
15.

Ainsliadimer A Induces ROS-Mediated Apoptosis in Colorectal Cancer Cells via Directly Targeting Peroxiredoxin 1 and 2

Chao Lv
Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology
Yun Huang
Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology
Posted: 22 Apr 2022
Publication Status: Under Review
Downloads 3
16.

Identification and Characterization of a Novel Brain-Penetrant Indoleamine 2,3 Dioxygenase 1 Protein Degrader for Glioblastoma

Lakshmi Bollu
affiliation not provided to SSRN
Prashant V. Bommi
affiliation not provided to SSRN
Posted: 11 Apr 2022
Publication Status: Review Complete
Downloads 12
17.

The Small GTPase RAB18 Recruits CUL3 Ubiquitin E3 Ligase to Lipid Droplets During Adipogenesis

Dawadschargal Dubiel
Otto-von-Guericke-Universität Magdeburg - Institute of Experimental Internal Medicine
Jing Wang
Xiamen University - School of Pharmaceutical Sciences
Posted: 08 Apr 2022
Publication Status: Review Complete
Downloads 6
18.

Investigating the NRAS 5' UTR as a Target for Small Molecules

Sumirtha Balaratnam
National Cancer Institute - Chemical Biology Laboratory
Zachary Torrey
National Cancer Institute - Chemical Biology Laboratory
Posted: 01 Apr 2022
Publication Status: Review Complete
Downloads 7
19.

Targeted Degradation of PCNA Outperforms Stoichiometric Inhibition to Result in Programed Cell Death

Shih Chieh Chang
affiliation not provided to SSRN
Pooja Gopal
affiliation not provided to SSRN
Posted: 23 Mar 2022
Publication Status: Published
Downloads 4
20.

Ginseng-Derived Panaxadiol Ameliorates STZ-Induced Type 1 Diabetes Through Inhibiting RORγ/IL-17A Axis

Siyu Tian
Xiamen University - State Key Laboratory of Cellular Stress Biology
Shuming Chen
Xiamen University - State Key Laboratory of Cellular Stress Biology
Posted: 01 Mar 2022
Publication Status: Review Complete
Downloads 6