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Cell Stem Cell

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Viewing: 1 - 18 of 18 papers

1.

Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity

Number of pages: 58 Posted: 07 Apr 2018
Working Paper Series
Salk Institute for Biological Studies - Gene Expression Laboratory, Salk Institute for Biological Studies - Gene Expression Laboratory, Sanford Consortium for Regenerative Medicine, Salk Institute for Biological Studies - Gene Expression Laboratory, Salk Institute for Biological Studies - Gene Expression Laboratory, Salk Institute for Biological Studies - Gene Expression Laboratory, Sanford Consortium for Regenerative Medicine and Salk Institute for Biological Studies - Gene Expression Laboratory
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2.

Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Number of pages: 73 Posted: 05 Apr 2018
Working Paper Series
Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Biological Regulation, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Molecular Genetics, Technion-Israel Institute of Technology - Department of Pediatrics and the Pediatric Immunology Unit, Broad Institute, European Bioinformatics Institute - Wellcome Genome Campus, Hebrew University of Jerusalem - Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem - Department of Developmental Biology and Cancer Research, Stanford University - Department of Applied Physics, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Weizmann Institute of Science - Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science - Department of Immunology, Weizmann Institute of Science - Department of Molecular Genetics and Weizmann Institute of Science - Department of Molecular Genetics
Downloads 16
3.

Cardiac Directed Differentiation Using Small Molecule WNT Modulation at Single-Cell Resolution

Number of pages: 49 Posted: 13 Apr 2018
Working Paper Series
University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland - Centre for Cardiac and Vascular Biology, Chinese Academy of Sciences (CAS) - Key Laboratory of Computational Biology, Chinese Academy of Sciences (CAS) - Key Laboratory of Computational Biology, Children's Medical Research Institute (CMRI) - Embryology Unit, Chinese Academy of Sciences (CAS) - State Key Laboratory of Cell Biology, Chinese Academy of Sciences (CAS) - State Key Laboratory of Cell Biology, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience, University of Washington - Department of Pathology, University of Queensland - School of Biomedical Sciences, Carnegie Mellon University - Computational Biology Department, University of Washington - Department of Pathology, University of Queensland - Centre for Cardiac and Vascular Biology, Carnegie Mellon University - Computational Biology Department, Children's Medical Research Institute (CMRI) - Embryology Unit, University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and University of Queensland, Faculty of Science, School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience
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4.

Comparison of Hematopoietic Stem Cell Expansion Methods Reveals That Aryl Hydrocarbon Receptor Inhibition Optimally Expands CD90 Engrafting Cells

Number of pages: 33 Posted: 02 Apr 2018
Working Paper Series
Magenta Therapeutics, Magenta Therapeutics, Magenta Therapeutics, Magenta Therapeutics, Magenta Therapeutics, Magenta Therapeutics, Magenta Therapeutics and Magenta Therapeutics
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5.

Generation of Esophageal Organoids from Human Pluripotent Stem Cells and Their Use to Study Human Development

Number of pages: 50 Posted: 10 Apr 2018
Working Paper Series
Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM) and Cincinnati Children's Hospital Medical Center - Center for Stem Cell & Organoid Medicine (CuSTOM)
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6.

Human iPSC-Derived RPE and Retinal Organoids Reveal Impaired Alternative Splicing of Genes Involved in Pre-mRNA Splicing in PRPF31 Autosomal Dominant Retinitis Pigmentosa Type 11

Number of pages: 55 Posted: 12 Apr 2018
Working Paper Series
Newcastle University (UK) - Institute of Genetic Medicine, Shenandoah University, Newcastle University (UK) - Institute of Genetic Medicine, University of Leeds - Leeds Institute of Biomedical & Clinical Sciences (LIBACS), Max Planck Institute for Biophysical Chemistry, Durham University - Department of Biological Sciences, University of Leeds - MRC Medical Bioinformatics Centre, Newcastle University (UK) - Institute of Genetic Medicine, Harvard University - Department of Ophthalmology, Harvard University - Department of Ophthalmology, State University of New York at Buffalo - Department of Ophthalmology, Newcastle University (UK) - Institute of Neuroscience, Newcastle University (UK) - Electron Microscopy Research Services, Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Institute for Cell and Molecular Biosciences, Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Interdisciplinary Computing and Complex BioSystems (ICOS), Newcastle University (UK) - Interdisciplinary Computing and Complex BioSystems (ICOS), Durham University - Department of Biological Sciences, King Abdul Aziz University - Princess Al Jawhara Al‐Brahim Center of Excellence in Research of Hereditary Disorders, King Abdul Aziz University - Princess Al Jawhara Al‐Brahim Center of Excellence in Research of Hereditary Disorders, Newcastle University (UK) - Institute of Genetic Medicine, University of the West of England (UWE) - Centre for Research in Biosciences, University of Leeds - Leeds Institute of Biomedical & Clinical Sciences (LIBACS), Newcastle University (UK) - Institute of Genetic Medicine, University of Leeds - Leeds Institute of Biomedical & Clinical Sciences (LIBACS), Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Institute of Genetic Medicine, London's Global University (UCL) - Institute of Opthalmology, Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Institute of Genetic Medicine, Newcastle University (UK) - Institute of Neuroscience, Harvard University - Ocular Genomics Institute, Max Planck Institute for Biophysical Chemistry, Durham University - Department of Biological Sciences, University of Leeds - Leeds Institute of Biomedical & Clinical Sciences (LIBACS) and Newcastle University (UK) - Institute of Genetic Medicine
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7.

Cross-Regulation Between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

Number of pages: 77 Posted: 05 Apr 2018
Working Paper Series
Helmholtz Zentrum München - Institute of Stem Cell Research (ISF), Cambridge Biomedical Campus - MRC Laboratory of Molecular Biology, Helmholtz Zentrum München - Institute of Stem Cell Research (ISF), Helmholtz Zentrum München - Institute of Stem Cell Research (ISF), Helmholtz Zentrum München - Institute of Stem Cell Research (ISF), Harvard University - Department of Stem Cell and Regenerative Biology, Helmholtz Zentrum München - Institute of Stem Cell Research (ISF), Jožef Stefan Institute - Department of Biotechnology, Helmholtz Zentrum München - Research Unit Protein Science (PROT), University of Zurich - Institute of Molecular Life Sciences, Harvard University - Department of Stem Cell and Regenerative Biology, Cambridge Biomedical Campus - MRC Laboratory of Molecular Biology and Helmholtz Zentrum München - Institute of Stem Cell Research (ISF)
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8.

Disruption of the TFAP2A Regulatory Domain Causes Banchio-Oculo-Facial Syndrome (BOFS) and Illuminates Pathomechanisms for Other Human Neurocristopathies

Number of pages: 73 Posted: 09 Apr 2018
Working Paper Series
University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Copenhagen - Biotech Research and Innovation Centre (BRIC), Erasmus MC, University of Cologne - Center for Physiology and Pathophysiology, Heinrich Heine University Dusseldorf - Duesseldorf Institute for Competition Economics (DICE), University of Cologne - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Southampton - Department of Human Genetics and Genomic Medicine, University of Exeter - Institute of Biomedical and Clinical Science and University of Cologne - Center for Molecular Medicine Cologne (CMMC)
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9.

Efficient Derivation of Basal Progenitor Cells from Human Pluripotent Stem Cells for Modeling Esophageal Development

Number of pages: 43 Posted: 13 Apr 2018
Working Paper Series
Columbia University - Division of Digestive and Liver Diseases, Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Division of Digestive and Liver Diseases, Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Department of Ophthalmology, Columbia University - Division of Digestive and Liver Diseases, Columbia University - Division of Digestive and Liver Diseases, Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Columbia Center for Human Development (CCHD), Leiden University - Department of Anatomy and Embryology, Leiden University - Department of Anatomy and Embryology, Columbia University - Columbia Center for Human Development (CCHD), Columbia University - Department of Ophthalmology, Columbia University - Columbia Center for Human Development (CCHD) and Columbia University - Division of Digestive and Liver Diseases
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10.

Human iPSC-Derived Hypothalamic Neurons from Super Obese Patients Exhibit Obesogenic Transcriptional Profiles and Dysregulated Hormone Responses

Number of pages: 48 Posted: 10 Apr 2018
Working Paper Series
Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, University of California, Irvine - Vawter Functional Genomics Laboratory, University of California, Irvine - Vawter Functional Genomics Laboratory, University of California, Irvine - Vawter Functional Genomics Laboratory, Cedars-Sinai Medical Center - Genomics Core, Cedars-Sinai Medical Center - Genomics Core, Cedars-Sinai Medical Center - Metabolism and Mitochondrial Research Core, Cedars-Sinai Medical Center - Metabolism and Mitochondrial Research Core and Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute
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11.

Chromatin Accessibility Dynamics During Reprogramming

Number of pages: 37 Posted: 04 Apr 2018
Working Paper Series
Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology, Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology and Chinese Academy of Social Sciences (CASS) - Key Laboratory of Regenerative Biology
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12.

Identification and Co-Targeting of EphA2/EphA3 Cancer Stem Cells in Recurrent Human Glioblastoma

Number of pages: 41 Posted: 06 Apr 2018
Working Paper Series
McMaster University - Stem Cell and Cancer Research Institute, McMaster University - Stem Cell and Cancer Research Institute, McMaster University - Stem Cell and Cancer Research Institute, University of Toronto - The Donnelly Centre, McMaster University - Stem Cell and Cancer Research Institute, University of Toronto - The Donnelly Centre, University of Toronto - The Donnelly Centre, University of Toronto - The Donnelly Centre, McMaster University - Stem Cell and Cancer Research Institute, University of Toronto - The Donnelly Centre, McMaster University - Stem Cell and Cancer Research Institute, University of Toronto - The Hospital for Sick Children- SickKids, McMaster University - Stem Cell and Cancer Research Institute, University of Toronto - The Hospital for Sick Children- SickKids, University of Toronto - The Donnelly Centre, McMaster University - Department of Surgery, University of Toronto - The Donnelly Centre, University of Toronto - The Hospital for Sick Children- SickKids, University of Toronto - The Donnelly Centre, University of Toronto - The Donnelly Centre and McMaster University - Stem Cell and Cancer Research Institute
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13.

Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene Networks

Number of pages: 55 Posted: 06 Jun 2018
Working Paper Series
Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Neuroscience, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research - Department of Neuroscience and Novartis Institutes for Biomedical Research - Department of Neuroscience
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14.

KMT2B Is Selectively Required for Direct Neuronal Reprogramming and Its Loss Exposes Dystonia-Relevant Targets

Number of pages: 67 Posted: 11 Apr 2018
Working Paper Series
European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics, European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics, Helmholtz Zentrum München - Institut für Neurogenomik, European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics, European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics, European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics, San Raffaele Hospital - San Raffaele Scientific Institute, Medical University Innsbruck - Department of Neurology, Charles University in Prague - Center of Clinical Neuroscience, Technische Universität München (TUM) - Klinik und Poliklinik für Neurologie, San Raffaele Hospital - San Raffaele Scientific Institute, Technische Universität München (TUM) - Institut für Humangenetik, Helmholtz Zentrum München - Institut für Neurogenomik and European Institute of Oncology (IEO) - Laboratory of Stem Cell Epigenetics
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15.

Cell Type of Origin Dictates the Route to Pluripotency

Number of pages: 54 Posted: 09 Apr 2018
Working Paper Series
Monash University - Department of Anatomy and Developmental Biology, Monash University - Department of Anatomy and Developmental Biology, Monash University - Department of Anatomy and Developmental Biology, Monash University - Department of Anatomy and Developmental Biology, Monash University - School of Biomedical Sciences, Monash University - Department of Anatomy and Developmental Biology, Monash University - Department of Anatomy and Developmental Biology, The University of Western Australia - ARC Center of Excellence in Plant Energy Biology, The University of Western Australia - ARC Center of Excellence in Plant Energy Biology, Monash University - Department of Anatomy and Developmental Biology, Monash University - Australian Regenerative Medicine Institute (ARMI), Monash University - Department of Anatomy and Developmental Biology, Monash University - Department of Anatomy and Developmental Biology, National University of Singapore (NUS) - Cardiovascular and Metabolic Disorders (CVMD), Monash University - Australian Regenerative Medicine Institute (ARMI), The University of Western Australia - ARC Center of Excellence in Plant Energy Biology, Monash University - Development and Stem Cells Program, Monash University - Monash Bioinformatics Platform, National University of Singapore (NUS) - Cardiovascular and Metabolic Disorders (CVMD) and Monash University - Department of Anatomy and Developmental Biology
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16.

Structurally Conserved Primate lncRNAs Are Transiently Expressed During Human Cortical Differentiation and Influence Cell Type Specific Genes

Number of pages: 59 Posted: 13 Apr 2018
Working Paper Series
University of California, Santa Cruz - Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Genomics Institute, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz - Department of Molecular, Cell, and Developmental Biology, Howard Hughes Medical Institute (HHMI), University of California, Santa Cruz - Genomics Institute, University of California, Santa Cruz - Genomics Institute, University of California, Santa Cruz - Genomics Institute and University of California, Santa Cruz - Genomics Institute
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17.

Latrophilin 2 Specifies Cardiac Lineage Commitment and Heart Development

Number of pages: 81 Posted: 10 Apr 2018
Working Paper Series
Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche, Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche, Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche, Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche, Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche, Dongguk University, College of Science and Technology, Department of Biomedical Engineering, Lab of Stem Cells and Cell Reprogramming, Dongguk University, College of Science and Technology, Department of Biomedical Engineering, Lab of Stem Cells and Cell Reprogramming and Seoul National University, College of Medicine, Department of Biomedical Sciences, National Research Laboratory for Stem Cell Niche
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18.

Single-Cell Sequencing Reveals CD133+CD44- – Originating Evolution and Stemness-Variants in AHNAK2, PLIN4, HLA-B, ALK, CCDC92 and ALMS1 of Human Colorectal Cancer Stem Cells

Number of pages: 43 Posted: 06 Jun 2018
Working Paper Series
Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Beijing Novogene Bioinformatics Technology Co., Ltd - Novogene Bioinformatics Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Information Center, Hangzhou Cancer Hospital - Department of Pathology, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute, Hangzhou Cancer Hospital - Hangzhou Cancer Institute and Hangzhou Cancer Hospital - Hangzhou Cancer Institute
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