30,889 Authors 3,237 Papers

Preprints with The Lancet

Preprints with The Lancet is part of SSRN´s First Look, a place where journals and other research experts identify content of interest prior to publication. These preprint papers are not peer-reviewed and are posted here as part of a 12-month trial. Authors have either opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet, or submitted directly via SSRN. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. These papers should not be used for clinical decision making or reporting of research to a lay audience without indicating that this is preliminary research that has not been peer-reviewed. For more information see the Comment published in The Lancet, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com

Viewing: 1 - 20 of 302 papers

1.

Tumor Induced PD-L1 on Neutrophils Suppress the Antitumor Immunity of NK Cells via PD-L1/PD-1 Axis

Rui Sun
Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Oncology
Ying-Ying Xiong
Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Clinical Laboratory
Posted: 04 Jan 2019
Downloads 39
2.

Epacadostat Plus Pembrolizumab versus Placebo Plus Pembrolizumab in Patients with Unresectable or Metastatic Melanoma: Results of the Phase 3, Randomised, Double-Blind Echo-301/Keynote-252 Study

Georgina Long
The University of Sydney - Melanoma Institute Australia
Reinhard Dummer
University Hospital Zurich
Posted: 05 Feb 2019
Downloads 30
3.

Allogeneic Amniotic Membrane-Derived 3-Dimensional Culture of Mesenchymal Stem Cells Promotes Rapid Burn Wound Closure in a Non-Human Primate Burn Wound Injury Model

Rachmawati Noverina
Padjadjaran University - Faculty of Medicine
Ahmad Faried
Padjadjaran University - Faculty of Medicine
Posted: 17 Mar 2019
Downloads 24
4.

SA-49, a Novel Aloperine Derivative, Induces MITF-Dependent Lysosomal Degradation of PD-L1

Na Zhang
Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology
Yueying Dou
Hefei BOE Hospital Co., Ltd
Posted: 04 Dec 2018
Downloads 24
5.

Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Are Critical Features of MODY: Lessons from a 5-Year Paediatric Swedish National Cohort Study

A. Carlsson
Lund University - Skåne University Hospital
M. Shepherd
University of Exeter - Institute of Biomedical and Clinical Science
Posted: 28 Jan 2019
Downloads 21
6.

Axitinib in Combination with Toripalimab, a Humanized IgG4 mAb Against Programmed Death-1 (PD-1) in Patients with Metastatic Mucosal Melanoma: A Non-Randomized, Open-Label, Dose-Finding, and Cohort-Expansion Phase 1b Trial

Xinan Sheng
Peking University - Key Laboratory of Carcinogenesis and Translational Research
Xieqiao Yan
Peking University - Key Laboratory of Carcinogenesis and Translational Research
Posted: 24 Jan 2019
Downloads 21
7.

Leveraging Transcriptional Dynamics to Improve BRAF Inhibitor Responses in Melanoma

Inna Smalley
H. Lee Moffitt Cancer Center and Research Institute - The Department of Tumor Biology
Eunjung Kim
H. Lee Moffitt Cancer Center and Research Institute - Department of Integrated Mathematical Oncology
Posted: 27 Jun 2019
Downloads 21
8.

Manifesting New Potential LncRNAs in Multiple Sclerosis Targeting Th1 Cell Lineage

Aref Hosseini
University of Isfahan
Shohreh Teimuri
Academic Center for Education, Culture and Research (ACECR)
Posted: 17 Sep 2018
Downloads 20
9.

PDRN, a Biologic Agonist of the Adenosine A 2A Receptor, Ameliorates Imiquimod-Induced Psoriasis Through NF-κB Pathway Inhibition and Wnt/β-Catenin Signalling Modulation

Natasha Irrera
University of Messina
Alessandra Bitto
University of Messina
Posted: 19 Feb 2019
Downloads 20
10.

Minimal Risk of HBV Reactivation in Resolved HBV-Infected Patients During Immunosuppressive Therapy

Yüksel Gümürdülü
Cukurova University, Faculty of Medicine, Internal Medicine, Department of Gastroenterology
Salih Tokmak
Cukurova University, Faculty of Medicine, Internal Medicine, Department of Gastroenterology
Posted: 12 Sep 2018
Downloads 18
11.

A Microfluidic ExoNANO for Efficient Isolation and Chemiluminescence Quantitative Immunoassay of Exosomes

Yiyun Wang
Zhejiang University
Zhenping Liu
Zhejiang University
Posted: 10 Dec 2018
Downloads 17
12.

Carrageenan Triggers NLRP3 Inflammasome Activation and IL-1β Production by Macrophages

Alexandre H. Lopes
University of Sao Paulo (USP) - Center for Research in Inflammatory Diseases (CRID)
Rangel L. Silva
University of Sao Paulo (USP) - Center for Research in Inflammatory Diseases (CRID)
Posted: 20 Jun 2019
Downloads 17
13.

Study of Clinical Profile and Immunological Dysfunction in One Hundred Patients of Recurrent Dermatophytosis

Krishna Jha
Postgraduate Institute of Medical Education and Research - Department of Dermatology, Venereology and Leprology
Tarun Narang
Postgraduate Institute of Medical Education and Research - Department of Dermatology, Venereology and Leprology
Posted: 08 Jan 2019
Downloads 17
14.

Influenza Immunoglobulin for Adults Hospitalized with Influenza

Richard T. Davey
Government of the United States of America - National Institute of Allergy and Infectious Diseases (NIAID)
Eduardo Fernandez-Cruz
Gregorio Marañón Hospital
Posted: 05 Apr 2019
Downloads 15
15.

Lactobacillus Casei Protects Dextran Sodium Sulfate- or Rapamycin-Induced Colonic Inflammation in the Mouse

Yong Zhang
Inner Mongolia Agricultural University - Key Laboratory of Dairy Biotechnology and Engineering
Qiangchuan Hou
Inner Mongolia Agricultural University - Key Laboratory of Dairy Biotechnology and Engineering
Posted: 10 Sep 2018
Downloads 15
16.

Efficacy and Safety of Oral Janus Kinase Inhibitors for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Christopher Ma
University of Calgary - Division of Gastroenterology & Hepatology
Jeffrey K. Lee
Kaiser Permanente
Posted: 20 Feb 2019
Downloads 14
17.

p16INK4A-Expressing Mesenchymal Stromal Cells Restore the Senescence-Clearance-Regeneration Sequence that is Impaired in Chronic Muscle Inflammation

Takako Saito-Chikenji
Sapporo Medical University - Department of Anatomy
Yuki Saito
Sapporo Medical University
Posted: 10 Jan 2019
Downloads 14
18.

Systematic Analysis of the Clinical Significance, Molecular Characterization, and Potential Targeted Agents of Immune-Related Genes in Hepatocellular Carcinoma

Peng Lin
Guangxi Medical University - Department of Medical Ultrasonics
Xiao-dong Wang
Guangxi Medical University - Department of Medical Ultrasonics
Posted: 12 Sep 2018
Downloads 14
19.

A Network Meta-Analysis of Vaccination Schedules and the Effect on Humoral and Intestinal Immunity Against Poliovirus

Grace Macklin
London School of Hygiene and Tropical Medicine - Department of Disease Control
Nicholas C Grassly
Imperial College London
Posted: 04 Dec 2018
Downloads 13
20.

A New Serological Method for the Differential Diagnosis of Hashimoto's Thyroiditis and Graves' Disease

Biao Huang
Zhejiang Sci-tech University
Yi Zhang
Nanjing Medical University - Jiangsu Institute of Nuclear Medicine
Posted: 08 Nov 2018
Downloads 13