30,440 Authors 3,185 Papers

Preprints with The Lancet

Preprints with The Lancet is part of SSRN´s First Look, a place where journals and other research experts identify content of interest prior to publication. These preprint papers are not peer-reviewed and are posted here as part of a 12-month trial. Authors have either opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet, or submitted directly via SSRN. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. These papers should not be used for clinical decision making or reporting of research to a lay audience without indicating that this is preliminary research that has not been peer-reviewed. For more information see the Comment published in The Lancet, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com

Viewing: 1 - 20 of 826 papers

1.

Aberrant Axon Branching Via Fos-B Dysregulation in FUS-ALS Motor Neurons

Tetsuya Akiyama
Tohoku University - Graduate School of Medicine
Naoki Suzuki
Tohoku University - Graduate School of Medicine
Posted: 06 Dec 2018
Downloads 83
2.

Restoration of Osteogenesis by CRISPR/Cas9 Genome Editing of the Mutated COL1A1 Gene in Osteogenesis Imperfecta

Hyerin Jung
Catholic University of Korea
Narae Park
Catholic University of Korea
Posted: 28 Jan 2019
Downloads 74
3.

Genetic and Environmental Risk Factors for Alcoholism: A 16-Year Longitudinal Cohort Study

I-Chao Liu
Fu Jen University Hospital
Shu-Fen Liao
National Taiwan University - Graduate Institute of Epidemiology and Preventive Medicine
Posted: 20 Feb 2019
Downloads 69
4.

PLCG2 Protective Variant p.P522R Modulates Tau Pathology and Disease Progression in Patients with Mild Cognitive Impairment

Luca Kleineidam
University of Cologne - Division of Neurogenetics and Molecular Psychiatry
Vincent Chouraki
University of Lille II - RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases
Posted: 02 Jan 2019
Downloads 55
5.

Genetic Features and Efficacy of Decitabine-Based Chemotherapy in Elderly Patients with Acute Myeloid Leukemia

Bianhong Wang
Tsinghua University - Beijing Tsinghua Changgung Hospital
Na Lv
Government of the People's Republic of China - Chinese General Hospital
Posted: 21 Sep 2018
Downloads 51
6.

Ampicillin-Eating, Carbapenem-Resistant, Super-Superbug Pseudomonas sp. MR 02, Isolated from an Indian River, Mahananada, Has Exhaustive Repertoire of Genes to Combat All Classes of Antibiotics and Catabolize β-Lactams for Its Sustenance

Vivek Kumar Ranjan
University of North Bengal - OMICS Laboratory
Shriparna Mukherjee
University of North Bengal - OMICS Laboratory
Posted: 07 Jun 2019
Downloads 50
7.

VPS35 Interacts with Dopamine Transportor and Disrupts Dopamine Transporter Recycling Pathway

Yi Huang
Sun Yat-Sen University (SYSU) - Department of Neurology
Leping Zhou
Sun Yat-Sen University (SYSU) - Department of Neurology
Posted: 16 Jan 2019
Downloads 43
8.

Brain Morphological Analysis in PTEN Hamartoma Tumor Syndrome

Tadashi Shiohama
Harvard University - Division of Newborn Medicine
Jacob Levman
Harvard University - Division of Newborn Medicine
Posted: 20 Nov 2018
Downloads 36
9.

Bridging of Neisseria Gonorrhoeae Across Diverse Sexual Networks in the HIV Pre-Exposure Prophylaxis (PrEP) Era: A Clinical and Molecular Epidemiological Study

Deborah Williamson
University of Melbourne - Microbiological Diagnostic Unit Public Health Laboratory
Eric P. F. Chow
Alfred Health - Melbourne Sexual Health Centre
Posted: 04 Feb 2019
Downloads 36
10.

Direct Transmission of Within-Host Mycobacterium Tuberculosis Diversity to Secondary Cases Can Lead to Variable Between-Host Heterogeneity Without De Novo Mutation: A Genomic Investigation

Marie Séraphin
University of Florida - Division of Infectious Diseases and Global Medicine
Anders Norman
Statens Serums Institut
Posted: 09 May 2019
Downloads 35
11.

Detection of New Crimean-Congo Hemorrhagic Fever Virus Genotypes in Ticks Feeding on Deer and Wild Boar, Spain

Alberto Moraga-Fernández
Instituto de Investigación en Recursos Cinegéticos IREC
Lara Royo-Hernández
Instituto de Investigación en Recursos Cinegéticos IREC
Posted: 16 Jan 2019
Downloads 32
12.

Construction and Comprehensive Analysis of a Competitive Endogenous RNA Network and Potential Regulatory Axes in Gastric Cancer

Hongda Pan
Fudan University - Department of Gastric Surgery
Jingxin Pan
Fujian Medical University
Posted: 12 Apr 2019
Downloads 30
13.

Blood DNA Methylation Biomarkers of Cumulative Lead Exposure in Adults

Elena Colicino
Mount Sinai Health System - Icahn School of Medicine
Allan Just
Mount Sinai Health System - Icahn School of Medicine
Posted: 02 Mar 2019
Downloads 28
14.

Whole Genome Sequence Analysis of Intensively Ill Children: A Prospective Study of Parent-Child Trios in the UK

Courtney E French
University of Cambridge
Isabelle Delon
NHS Foundation Trust - Cambridge University Hospitals
Posted: 08 Oct 2018
Downloads 28
15.

A Genome-wide Study of DNA Methylation in Nasal Epithelium and Atopy and Atopic Asthma in Children

Erick Forno
University of Pittsburgh - Department of Pediatrics
Ting Wang
University of Pittsburgh - School of Medicine
Posted: 06 Nov 2018
Downloads 27
16.

Genetic Predisposing Variants Associated with Cancer Therapy-Induced Cardiomyopathy

Pablo Garcia-Pavia
Hospital Universitario Puerta de Hierro-Majadahonda, Department of Cardiology, Heart Failure and Inherited Cardiac Diseases Unit
Yuri Kim
Harvard University - Harvard Medical School
Posted: 26 Sep 2018
Downloads 27
17.

EF Derived from Human Placental Mesenchymal Stem Cells Improves Premature Ovarian Insufficiency Via NRF2/HO-1 Activation

Chenyue Ding
Nanjing Medical University - Center of Reproduction and Genetics
Qinyan Zou
Nanjing Medical University - Center of Reproduction and Genetics
Posted: 16 Jan 2019
Downloads 26
18.

Pan-Cancer Analysis Reveals Synergistic Effects of CDK4/6i and PARPi Combination Treatment in RB-Proficient and RB-Deficient Breast Cancer Cells

Songyu Li
Dalian University - Dalian Medical University
Xiaoyan Wu
Dalian University - Dalian Medical University
Posted: 07 Nov 2018
Downloads 25
19.

A Nonsynonymous Mutation in PLCG2 Reduces the Risk of Alzheimer's Disease, Dementia with Lewy-Bodies and Frontotemporal Dementia, and Increases the Likelihood of Longevity

Sven J. van der Lee
VU University Amsterdam
Olivia J. Conway
Mayo Clinic - Florida
Posted: 01 Feb 2019
Downloads 24
20.

Development and Implementation of the Sickle Cell Disease Ontology

Nicola Mulder
University of Cape Town (UCT) - Computational Biology Division
Ambroise Wonkam
University of Cape Town (UCT) - Division of Human Genetics
Posted: 14 Feb 2019
Downloads 24