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BiochemRN: Small Molecules (Topic)

222 Total downloads

Viewing: 1 - 18 of 18 papers

1.

Hair Regeneration by Small Molecules That Activate Autophagy

Number of pages: 21 Posted: 01 Jun 2018
Working Paper Series
University of California, Los Angeles (UCLA) - Molecular Biology Interdisciplinary Graduate Program, University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), University of California, Los Angeles (UCLA) - Department of Human Genetics, University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), University of California, Los Angeles (UCLA) - Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), University of California, Los Angeles (UCLA) - Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA) - Department of Human Genetics and University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP)
Downloads 52
2.

Cardiac Directed Differentiation Using Small Molecule WNT Modulation at Single-Cell Resolution

Number of pages: 49 Posted: 13 Apr 2018
Working Paper Series
University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Centre for Cardiac and Vascular Biology, Chinese Academy of Sciences (CAS) - Key Laboratory of Computational Biology, Chinese Academy of Sciences (CAS) - Key Laboratory of Computational Biology, Children's Medical Research Institute (CMRI) - Embryology Unit, Chinese Academy of Sciences (CAS), Shanghai Institutes for Biological Sciences, Institute of Biochemistry and Cell Biology, State Key Laboratory of Cell Biology, Chinese Academy of Sciences (CAS) - Institute of Biochemistry and Cell Biology, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Washington - Department of Pathology, University of Queensland - School Biomedical Science, Carnegie Mellon University - Computational Biology Department, University of Washington - Department of Pathology, University of Queensland - Centre for Cardiac and Vascular Biology, Carnegie Mellon University - Computational Biology Department, Children's Medical Research Institute (CMRI) - Embryology Unit, University of Queensland - Institute for Molecular Bioscience and University of Queensland - Institute for Molecular Bioscience
Downloads 23
3.

SA-49, a Novel Aloperine Derivative, Induces MITF-Dependent Lysosomal Degradation of PD-L1

Number of pages: 46 Posted: 04 Dec 2018
Working Paper Series
Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Hefei BOE Hospital Co., Ltd, Qingdao University, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology and Chinese Academy of Medical Sciences - Institute of Medicinal Biotechnology
Downloads 22
4.

Cheminformatics Tools for Analyzing and Designing Optimized Small Molecule Collections and Libraries

Number of pages: 45 Posted: 30 May 2019
Working Paper Series
Harvard University - Department of Systems Biology, University of Cincinnati - Division of Biostatistics and Bioinformatics, Harvard University - Department of Systems Biology, Novartis Institutes for Biomedical Research, Novartis Institutes for Biomedical Research, University of Cincinnati - Division of Biostatistics and Bioinformatics, Harvard University - Department of Cancer Biology, Dana-Farber/Harvard Cancer Center - Department of Cancer Biology, Novartis Institutes for Biomedical Research and Harvard University - Department of Systems Biology
Downloads 15
5.

Efficacy and Safety of Oral Janus Kinase Inhibitors for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Number of pages: 47 Posted: 20 Feb 2019
Working Paper Series
University of Calgary - Division of Gastroenterology & Hepatology, Kaiser Permanente, University of British Columbia (UBC), University of California San Diego, University of Calgary, Robarts Clinical Trials, Inc., University of California San Diego, Western University, University of Calgary, Robarts Clinical Trials, Inc. and Robarts Clinical Trials, Inc.
Downloads 11
6.

Small Molecule Mediated Intervention of NF-kB or TGF-β Signaling Reverses Age-Related Phenotypes in Satellite Cells and Enhances Muscle Repair

Number of pages: 42 Posted: 06 Sep 2018
Working Paper Series
Harvard University - Department of Stem Cell and Regenerative Biology, Harvard University - Department of Stem Cell and Regenerative Biology, Joslin Diabetes Center - Bioinformatics Core, GlaxoSmithKline - Target and Pathway Validation Unit, GlaxoSmithKline - Regenerative Medicine Discovery Performance Unit, GlaxoSmithKline - Metabolism Discovery Performance Unit, GlaxoSmithKline - Metabolism Discovery Performance Unit, GlaxoSmithKline - Metabolic Pathways and Cardiovascular Therapeutic Area Unit, Joslin Diabetes Center - Genomics Core, Stanford University - Institute for Stem Cell Biology and Regenerative Medicine, Harvard University - Department of Stem Cell and Regenerative Biology, Stanford University - Institute for Stem Cell Biology and Regenerative Medicine and Harvard University - Department of Stem Cell and Regenerative Biology
Downloads 11
7.

Therapeutic Potential of an Orally Available Dual Small-Molecule Modulator of Wnt and P53 Pathways in Neovascular Age-Related Macular Degeneration

Number of pages: 39 Posted: 28 Nov 2018
Working Paper Series
Kookmin University, Konkuk University, Kookmin University, Kyungpook National University, Kookmin University, Kookmin University, Konkuk University, Kyungpook National University, Chungnam National University, Chungnam National University, Chungnam National University - College of Pharmacy, Konkuk University - Department of Ophthalmology and Kookmin University - Department of Bio and Fermentation Convergence Technology
Downloads 11
8.

A Simple Egg Membrane Model for Understanding Diffusion Characteristics of Nanoparticles and Amino Acids

Number of pages: 12 Posted: 05 Jul 2017
Working Paper Series
University of Mumbai, University of Mumbai, University of Mumbai, University of Mumbai, University of Mumbai, University of Mumbai and University of Mumbai
Downloads 10
9.

Pulmonary Adverse Events of Small Molecule Tyrosine Kinase Inhibitors: Meta-Analysis and Systematic Review

Number of pages: 36 Posted: 05 Mar 2019 Last Revised: 11 Mar 2019
Working Paper Series
Alfred Hospital, Alfred Hospital, Monash University - Central Clinical School, Alfred Hospital and Monash University - Central Clinical School
Downloads 10
10.

Symbionts Exploit Complex Signaling to Educate the Immune System

Number of pages: 55 Posted: 01 Apr 2019
Working Paper Series
Harvard Medical School - Division of Immunology, Harvard University - Center for Experimental Therapeutics and Reperfusion Injury, Harvard Medical School - Division of Immunology, Harvard Medical School - Division of Immunology, Harvard Medical School - Division of Immunology, Max Planck Institute of Colloids and Interfaces - Department of Biomolecular Systems, Janssen Research & Development, LLC and Harvard Medical School - Division of Immunology
Downloads 9
11.

The Effects of Polyethylene Glycol (Peg-600) on the Acute Neurotoxicity of Different Types of Pesticides

International Journal of Management Sciences and Business Research. Vol 2:7, 2013
Number of pages: 11 Posted: 11 Jul 2017
Accepted Paper Series
King Abdulaziz University - Biology Department, King Abdulaziz University - Biology Department and King Abdulaziz University - Women Branch Khulais, Faculty of Science and Arts, Biology Department
Downloads 9
12.

The Asymmetric Expression of SAUR Genes Mediated by ARF7/19 Promotes the Gravitropism and Phototropism of Plant Hypocotyls

CELL-REPORTS-D-19-02175
Number of pages: 39 Posted: 09 Jun 2019
Working Paper Series
Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research, Peking University - State Key Laboratory of Protein and Plant Gene Research and Peking University - State Key Laboratory of Protein and Plant Gene Research
Downloads 8
13.

Treatment of Obesity-Related Inflammation with a Novel Synthetic Pentacyclic Oleanane Triterpenoids via Modulation of Macrophages Polarization

Number of pages: 42 Posted: 17 Mar 2019
Working Paper Series
Nanjing University, Nanjing University, Nanjing University, Nanjing University, Nanjing University, Nanjing University - Department of General Surgery, Nanjing University, Peking University, China Pharmaceutical University and Nanjing University - Affiliated Drum Tower Hospital
Downloads 8
14.

Optimal Linker Length for Small Molecule PROTACs that Selectively Target P38α and P38β for Degradation

CELL-CHEMICAL-BIOLOGY-D-19-00216
Number of pages: 50 Posted: 03 Jul 2019
Working Paper Series
The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona) and The Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona)
Downloads 6
15.

IODVA1, a Guanidinobenzimidazole Derivative with in vivo Activity Against Ras-Driven Cancer Models

CELL-CHEMICAL-BIOLOGY-D-19-00172
Number of pages: 62 Posted: 24 May 2019
Working Paper Series
Children’s Hospital Research Foundation - Division of Experimental Hematology and Cancer Biology, University of Cincinnati, University of Cincinnati, Cincinnati Children's Hospital Medical Center - Division of Biomedical Informatics, Children’s Hospital Research Foundation - Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Research Foundation, Children’s Hospital Research Foundation - Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati Children's Hospital Medical Center - Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Children’s Hospital Research Foundation - Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center and Children’s Hospital Research Foundation - Division of Experimental Hematology and Cancer Biology
Downloads 5
16.

A Novel Small Molecule Inhibitor of MDM2-p53 (APG-115) Has Antitumor Activity in Gastric Adenocarcinoma

Number of pages: 31 Posted: 29 Mar 2019
Working Paper Series
Sun Yat-Sen University (SYSU) - Department of Laboratory Medicine, Sun Yat-Sen University (SYSU) - Department of Experimental Research, Sun Yat-Sen University (SYSU) - Department of Experimental Research, Sun Yat-Sen University (SYSU), Sun Yat-Sen University (SYSU) - Department of Experimental Research, Sun Yat-Sen University (SYSU) - Department of Experimental Research, Sun Yat-Sen University (SYSU) - Department of Experimental Research, Sun Yat-Sen University (SYSU) - Department of Laboratory Medicine, Sun Yat-Sen University (SYSU) - Department of Medical Oncology and Sun Yat-Sen University (SYSU) - Department of Experimental Research
Downloads 4
17.

EGFR Signaling is the Major Regulator of Ecdysone Biosynthesis in the Drosophila Prothoracic Gland

CURRENT-BIOLOGY-D-19-01019
Number of pages: 32 Posted: 01 Jul 2019
Working Paper Series
Universitat Pompeu Fabra - Institute of Evolutionary Biology, Universitat Pompeu Fabra - Institute of Evolutionary Biology and Universitat Pompeu Fabra - Institute of Evolutionary Biology
Downloads 4
18.

Gradient Expression of Transcription Factor Imposes a Boundary on Organ Regenerative Potential in Plant

Number of pages: 24 Posted: 20 Mar 2019
Working Paper Series
Indian Institute of Science Education and Research - School of Biology, Indian Institute of Science Education and Research - School of Biology, Indian Institute of Science Education and Research - School of Biology, Indian Institute of Science Education and Research - School of Biology, Wageningen UR - Plant Developmental Biology, University of Helsinki - Institute of Biotechnology, Wageningen UR - Plant Developmental Biology and Indian Institute of Science Education and Research - School of Biology
Downloads 4