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Yanchen Guo

affiliation not provided to SSRN

  • affiliation not provided to SSRN

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Isthmin-1 is a Key Regulator of Induced Pluripotent Stem Cell–Derived Cardiomyocytes Maturation through Activation of p53 Signaling

Number of pages: 34 Posted: 05 Feb 2026
Haowen Guo, xin Zhou, Yang Shi, Jiaxian Wang, Bin Zhou, Jiaqi Tang, Faxiang Xu, Yanchen Guo, Fang Chen, Dongming Su and Qingguo Li
affiliation not provided to SSRN, Nanjing Medical University, affiliation not provided to SSRN, Nanjing Help Therapeutics Co Ltd., affiliation not provided to SSRN, Nanjing Medical University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Nanjing Medical University and affiliation not provided to SSRN
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cardiomyocyte maturation, iPSC-CMs, ISM1, p53 signaling, metabolic remodeling