affiliation not provided to SSRN, Wenzhou Medical University - Taizhou Hospital of Zhejiang Province, affiliation not provided to SSRN, East China University of Science and Technology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Hangzhou Normal University, affiliation not provided to SSRN, Wenzhou Medical University - Taizhou Hospital of Zhejiang Province, Xiamen University - Cancer Research Center, Xiamen University - Department of Medical Oncology, Xiamen University and Xiamen University