Jacob S. Sherkow

Harvard University

124 Mount Auburn St.

Cambridge, MA 02138

United States

http://https://scholar.harvard.edu/jsherkow

New York Law School

Professor of Law

185 West Broadway

New York, NY 10013

United States

http://www.nyls.edu/faculty/faculty-profiles/faculty_profiles/jacob-s-sherkow/

Center for Advanced Studies in Biomedical Innovation Law

Permanent Visiting Professor

Studiestraede 6

Studiestrade 6

Copenhagen, DK-1455

Denmark

http://jura.ku.dk/cebil/staff/

SCHOLARLY PAPERS

46

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13

CROSSREF CITATIONS

21

Scholarly Papers (46)

1.

What If Extinction is Not Forever?

Science, Vol. 340, pp. 32-33, April 2013, Stanford Public Law Working Paper No. 2298798
Number of pages: 2 Posted: 27 Jul 2013
Jacob S. Sherkow and Henry T. Greely
Harvard University and Stanford Law School
Downloads 456 (67,005)

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2.

Who Owns Gene Editing? Patents in the Time of CRISPR

Biochemist, Vol. 38, p. 26 (2016), NYLS Legal Studies Research Paper No. 2915853
Number of pages: 4 Posted: 16 Feb 2017
Jacob S. Sherkow
Harvard University
Downloads 329 (97,969)

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intellectual property, patent, biotech, biotechnology, crispr, genetics

3.

The History of Patenting Genetic Material

Annual Review of Genetics, Vol. 49, p. 161, 2015
Number of pages: 22 Posted: 11 Jan 2016
Jacob S. Sherkow and Henry T. Greely
Harvard University and Stanford Law School
Downloads 291 (112,035)
Citation 3

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4.

Patent Law's Reproducibility Paradox

Duke Law Journal, Vol. 66, pp. 845-911 (2017)
Number of pages: 67 Posted: 22 Feb 2016 Last Revised: 23 Jan 2017
Jacob S. Sherkow
Harvard University
Downloads 233 (140,740)

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patent, science, reproducibility, drugs, pharmaceuticals, enablement, utility, intellectual property, clinical tests

5.

The Natural Complexity of Patent Eligibility

Iowa Law Review, Vol. 99, p. 1137, 2014, Stanford Public Law Working Paper No. 2268180
Number of pages: 60 Posted: 22 May 2013 Last Revised: 03 Mar 2014
Jacob S. Sherkow
Harvard University
Downloads 219 (149,531)

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patent, nature, law, phenomena, product, complexity, decomposition, localization, multiprong, multifactor, science, technology, intellectual property

6.

Cancer's IP

North Carolina Law Review, 2018, Vol. 96, pp. 297-380, NYLS Legal Studies Research Paper No. 2928241
Number of pages: 84 Posted: 07 Mar 2017 Last Revised: 18 Jan 2018
Jacob S. Sherkow
Harvard University
Downloads 211 (154,795)

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Patent, Science, Cancer, Drugs, Pharmaceuticals, Information Policy, Privacy, Data-Sharing, Intellectual Property, Clinical Trials, Moonshot, Public-Private Partnerships

7.

The Future of Gene Patents and the Implications for Medicine

173 JAMA Internal Medicine 1569, Sept. 2013
Number of pages: 2 Posted: 15 Sep 2013 Last Revised: 25 Sep 2013
Jacob S. Sherkow and Henry T. Greely
Harvard University and Stanford Law School
Downloads 210 (155,433)
Citation 1

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gene, genetic, patent, intellectual property, myriad, amp, medicine, BRCA, cancer

8.

Administrating Patent Litigation

Washington Law Review, Vol. 90, p. 205, 2015, NYLS Legal Studies Research Paper No. 13/14 #84
Number of pages: 65 Posted: 26 Aug 2014 Last Revised: 14 May 2015
Jacob S. Sherkow
Harvard University
Downloads 205 (159,083)

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patent, admin, administrative, agencies, litigation, FTC, FCC, FDA, PTO

9.

Law, History and Lessons in the CRISPR Patent Conflict

Nature Biotechnology, Vol. 33, pp. 256-57, March 2015, NYLS Legal Studies Research Paper No. 2579609
Number of pages: 2 Posted: 17 Mar 2015
Jacob S. Sherkow
Harvard University
Downloads 194 (167,415)
Citation 2

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intellectual property, patent, biotech, biotechnology, crispr, genetics

10.

CRISPR, Patents, and the Public Health

Yale Journal of Biology and Medicine, vol. 90, pp. 667-672 (2017), NYLS Legal Studies Research Paper No. 3093610
Number of pages: 6 Posted: 03 Jan 2018 Last Revised: 28 Jan 2018
Jacob S. Sherkow
Harvard University
Downloads 180 (179,051)
Citation 1

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crispr, patents, public health, gene editing, drug pricing, insurance, research, regulation, law, policy

11.

23andMe, the Food and Drug Administration, and the Future of Genetic Testing

174 JAMA Internal Medicine E1-E2 (2014), Stanford Public Law Working Paper No. 2402877
Number of pages: 2 Posted: 01 Mar 2014
Patricia J. Zettler, Jacob S. Sherkow and Henry T. Greely
Ohio State University (OSU) - Michael E. Moritz College of Law, Harvard University and Stanford Law School
Downloads 171 (187,255)

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23andMe, genes, genetics, genetic testing, DTC, FDA, biotech, sequencing, DNA, health, law, science

12.

Inventive Steps: The CRISPR Patent Dispute and Scientific Progress

EMBO Reports, Vol. 18, pp. 1047-1050 (2017)
Number of pages: 5 Posted: 28 Jun 2017 Last Revised: 27 Dec 2017
Jacob S. Sherkow
Harvard University
Downloads 156 (202,596)

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patent, nonobviousness, invention, crispr, science, biotechnology, intellectual property, ipr, broad, berkeley, doudna, zhang, charpentier, licensing

13.

CRISPR, Surrogate Licensing, and Scientific Discovery

Science, Vol. 355, Issue 6326, pp. 698-700, Feb. 2017, University of Utah College of Law Research Paper No. 223
Number of pages: 4 Posted: 28 Jun 2017 Last Revised: 16 Aug 2017
Jorge L. Contreras and Jacob S. Sherkow
University of Utah - S.J. Quinney College of Law and Harvard University
Downloads 151 (208,153)

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Intellectual Property, Patent, Biotech, Biotechnology, CRISPR, Genetics, Surrogate, Licensing, Spinoff

14.

The Pick-and-Shovel Play: Bioethics for Gene-Editing Vector Patents

North Carolina Law Review, 2019, vol. 97, pp. 1497–1552
Number of pages: 56 Posted: 28 Nov 2018 Last Revised: 28 Jul 2019
Jacob S. Sherkow and Christopher Thomas Scott
Harvard University and Baylor University - Center for Medical Ethics and Health Policy
Downloads 142 (218,803)
Citation 1

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Patent, Gene-Editing, IP, CRISPR, ZFN, TALEN, Vector, Cell, Secret, Pick-and-Shovel, Arbitrage, Equipment, Ethics, Bioethics, Gene Therapy, Risk, Preclinical, Informed Consent, Drug Cost, Drug Price, Price, Cost, Disclosure, Consumer, Standards, SEPs, SSO

15.

Patent Infringement as Criminal Conduct

Michigan Telecommunications and Technology Law Review, Vol. 19, p. 1, 2012, Stanford Public Law Working Paper No. 2022067
Number of pages: 42 Posted: 15 Mar 2012 Last Revised: 19 Dec 2012
Jacob S. Sherkow
Harvard University
Downloads 142 (218,803)

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patent, criminal law, crime, infringement, inducement, technology, intent, global-tech, willful blindness

16.

Negativing Invention

Brigham Young University Law Review, Vol. 2011, pp. 1091-1138, 2011
Number of pages: 48 Posted: 24 Feb 2011 Last Revised: 10 Nov 2011
Jacob S. Sherkow
Harvard University
Downloads 140 (221,367)

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patent, invention, analogous art, negativing, technology, obviousness

17.

Letter to U.S. Senate Committee on the Judiciary Concerning Inter Partes Review and Orange Book-Listed Patents

Letter to the U.S. Senate Committee on the Judiciary, 2015
Number of pages: 3 Posted: 29 Jun 2015 Last Revised: 14 Jan 2016
Arti K. Rai and Jacob S. Sherkow
Duke University School of Law and Harvard University
Downloads 124 (243,159)

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patent, admin, administrative, agencies, litigation, FDA, PTO, IPR

18.

Patent Protection for CRISPR: An ELSI Review

Journal of Law and the Biosciences, Vol. 4 (2017) [lsx036], NYLS Legal Studies Research Paper No. 3093608
Number of pages: 12 Posted: 03 Jan 2018
Jacob S. Sherkow
Harvard University
Downloads 97 (289,081)

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CRISPR, patent, ELSI, science, collaboration, license, bioethics, competition, technology, genetics

19.

Intellectual Property, Surrogate Licensing, and Precision Medicine

IP Theory, Vol. 7 (2018), NYLS Legal Studies Research Paper No. 3106340
Number of pages: 20 Posted: 30 Jan 2018 Last Revised: 13 Nov 2019
Jacob S. Sherkow and Jorge L. Contreras
Harvard University and University of Utah - S.J. Quinney College of Law
Downloads 94 (294,971)
Citation 1

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intellectual property, patents, licenses, precision medicine, CRISPR, biologics, drugs

20.

Myriad Stands Alone

Nature Biotechnology, Vol. 32, p. 620, 2014, NYLS Legal Studies Research Paper No. 13/14 #83
Number of pages: 1 Posted: 26 Aug 2014
Jacob S. Sherkow and Christopher Thomas Scott
Harvard University and Baylor University - Center for Medical Ethics and Health Policy
Downloads 94 (294,971)
Citation 2

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myriad, gene, genetics, patent, intellectual property, biotechnology, supreme court

21.

The Changing Life Science Patent Landscape

Nature Biotechnology, vol. 34, pp. 292-93, Duke I&E Research Paper No. 2016-31
Number of pages: 3 Posted: 05 Jun 2016
Arti K. Rai and Jacob S. Sherkow
Duke University School of Law and Harvard University
Downloads 89 (305,222)
Citation 1

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patents, intellectual property, ip, AIA, PTO, bioscience, biotechnology, law, scotus, supreme court

22.

A Call for the End of the Doctrine of Realignment

Michigan Law Review, Vol. 107, No. 3, p. 525, 2008
Number of pages: 36 Posted: 03 Dec 2008 Last Revised: 10 Nov 2011
Jacob S. Sherkow
Harvard University
Downloads 84 (316,431)

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jurisdiction, diversity, realignment, federal courts, civil procedure, alignment, party alignment, joinder, indianapolis, chase national bank

23.

And How: Mayo v. Prometheus and the Method of Invention

Yale Law Journal Online, Vol. 122, p. 351, 2013, Stanford Public Law Working Paper No. 2296033
Number of pages: 8 Posted: 21 Jul 2013 Last Revised: 02 Aug 2013
Jacob S. Sherkow
Harvard University
Downloads 81 (323,474)

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patent, mayo, prometheus, invention, innovation, pto, intellectual property

24.

Protecting Products versus Platforms

Nature Biotechnology, Vol. 34, pp. 462-65, NYLS Legal Studies Research Paper No. 2789281
Number of pages: 4 Posted: 05 Jun 2016
Jacob S. Sherkow
Harvard University
Downloads 78 (330,646)

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patents, trade secrets, intellectual property, biotechnology, startups

25.

Finding a Regulatory Balance for Genetic Biohacking

Consuming Genetic Technologies: Ethical and Legal Considerations, Cambridge Univ. Press, Forthcoming
Number of pages: 11 Posted: 16 Dec 2019 Last Revised: 06 Apr 2020
Ohio State University (OSU) - Michael E. Moritz College of Law, Baylor College of Medicine and Harvard University
Downloads 76 (335,725)

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Biohacking, Biology, Science, Regulation, Autonomy, CRISPR, Embryos, Governance

26.

Stem Cell Patents after the America Invents Act

Cell Stem Cell, Vol. 16, pp. 461-464, 2015
Number of pages: 4 Posted: 15 May 2015
Jacob S. Sherkow and Christopher Thomas Scott
Harvard University and Baylor University - Center for Medical Ethics and Health Policy
Downloads 72 (346,047)

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patents, intellectual property, ip, AIA, PTO, cell, stem cell, bioscience, biotechnology, law, biogatekeeper, consumer watchdog, scotus, supreme court

27.

AIRR Data Under the E.U. Trade Secrets Directive: Aligning Scientific Practices with Commercial Realities

The Harmonization and Protection of Trade Secrets in the E.U. (Jens Schovsbo, Timo Minssen & Thomas Riis eds.) (Edward Elgar, 2019 Forthcoming), NYLS Legal Studies Research Paper No. 3249498
Number of pages: 23 Posted: 23 Oct 2018
Jacob S. Sherkow and Timo Minssen
Harvard University and University of Copenhagen - Centre for Advanced Studies in Biomedical Innovation Law (CeBIL) - Faculty of Law
Downloads 71 (348,753)

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AIRR, immune receptor, antibodies, TCRs, EU, trade secrets, science, genetic data, big data, follow-on data, patents, clinical trials, diagnostics

28.

Federal Trade Commission v. Actavis, Inc. and Reverse-Payment or Pay-for-Delay Settlements

Nature Biotechnology, Vol. 31, p. 316, 2013, Stanford Public Law Working Paper No. 2296187
Number of pages: 2 Posted: 20 Jul 2013 Last Revised: 26 Feb 2014
Jacob S. Sherkow
Harvard University
Downloads 66 (362,693)

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antitrust, patent, intellectual property, settlement, pharmaceutical, biotechnology

29.

Patent Protection for Microbial Technologies

FEMS Microbiology Letters, Vol. 364 [fnx205], 2017, NYLS Legal Studies Research Paper No. 3041221
Number of pages: 6 Posted: 25 Sep 2017 Last Revised: 27 Dec 2017
Jacob S. Sherkow
Harvard University
Downloads 65 (365,578)

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Patents; CRISPR; Virus; AMR; Incentives; Intellectual Property

30.

Preliminary Injunctions Post-Mayo and Myriad

Stanford Law Review Online, Vol. 67, pp. 1-8, 2014
Number of pages: 8 Posted: 13 Jun 2014
Jacob S. Sherkow
Harvard University
Downloads 62 (374,536)

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patents, biosciences, law, preliminary injunctions, civil procedure, litigation, mayo, myriad, supreme court, patentable subject matter, patent eligibility, section 101

31.

Patents, Promises, and Reproducibility

Georgetown Journal of International Law, 2018, Vol. 49, pp. 957-980
Number of pages: 24 Posted: 31 Mar 2017 Last Revised: 12 Sep 2018
Jacob S. Sherkow
Harvard University
Downloads 60 (380,642)

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patent, science, reproducibility, enablement, promise doctrine, industrial application, intellectual property, Canada, Europe

32.

The Science of Substitution: A Response to Carrier and Minniti

University of Illinois Law Review Online, vol. 2018, pp. 81-92 (2018), NYLS Legal Studies Research Paper No. 3093618
Number of pages: 12 Posted: 03 Jan 2018 Last Revised: 12 Apr 2018
Jacob S. Sherkow
Harvard University
Downloads 57 (390,306)

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33.

The Rise of the Ethical License

35 Nature Biotechnology 22 (2017)
Number of pages: 3 Posted: 13 Jan 2017 Last Revised: 16 Aug 2017
Baylor College of Medicine, Baylor College of Medicine, Harvard University and Baylor University - Center for Medical Ethics and Health Policy
Downloads 45 (432,559)
Citation 1

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patent, license, CRISPR, gene drives, NIPT, ethics, Broad Institute, Monsanto

34.

Key Challenges in Bringing CRISPR-Mediated Somatic Cell Therapy into the Clinic

Genome Medicine, 2017
Number of pages: 4 Posted: 18 Oct 2017
University of Tasmania, Georgetown University Law Center, University of Oxford - Centre for Health, Law and Emerging Technologies, Harvard University, University of Tasmania - Faculty of Law, University of Tasmania, University of Alberta - Faculty of Public Health, University of Tasmania, University of Tasmania - Faculty of Law, University of Manchester - Centre for Social Ethics and Policy, University of Tasmania - Menzies Institute for Medical Research, Swinburne University of Technology, University of New South Wales (UNSW), Flinders University, University of Tasmania, University of Tasmania, University of Cambridge - Faculty of Law, Addgene, Osaka, Dept of Biomedical Ethics & Public Policy, Graduate School of Medicine, McGill University, Kyoto University, The University of Western Australia, The University of Sydney, University of Tasmania, Geisinger Health System Inc. - Bioethics Research and University of Tasmania
Downloads 44 (436,447)

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Genome Editing, CRISPR, Somatic Cell Therapy, Genetic Diseases, Gene Therapy

35.

Bridges II: The Law–STEM Alliance & Next Generation Innovation

Northwestern University Law Review Online, Vol. 112, pp. 157-159 (2017), NYLS Legal Studies Research Paper No. 3091169
Number of pages: 3 Posted: 26 Dec 2017 Last Revised: 13 Aug 2018
Jacob S. Sherkow
Harvard University
Downloads 32 (488,365)

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CRISPR, cancer, law, stem, interdisciplinary, collaboration

36.

Pursuit of Profit Poisons Collaboration

Nature, vol. 532, pp. 172-173, NYLS Legal Studies Research Paper No. 2789283
Number of pages: 2 Posted: 05 Jun 2016 Last Revised: 13 Feb 2017
Jacob S. Sherkow
Harvard University
Downloads 30 (498,299)

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CRISPR, Cas9, patent, science, research, commercialization, technology, biotechnology, collaboration

37.

Describing Drugs: A Response to Professors Allison and Ouellette

Duke Law Journal Online, Vol. 65, pp. 127-147, 2016
Number of pages: 21 Posted: 17 May 2016
Jacob S. Sherkow
Harvard University
Downloads 29 (503,628)

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patents, intellectual property, ip, PTO, drugs, pharmaceuticals, bioscience, biotechnology, law, Allison, Ouellette, written description, 112, empirical, doctrinal

38.

Patent Eligibility Reform and the Public Health

The Milbank Quaterly, 2019, Vol. 97, pp. 654–658
Number of pages: 5 Posted: 27 Dec 2019
Jacob S. Sherkow
Harvard University
Downloads 22 (544,048)

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Myriad, public health, genetics, patent, § 101, medicine, diagnostics, reform, policy, legislation

39.

Is It 'Gene Therapy'?

Journal of Law and the Biosciences, Vol. 5, pp. 786–793, 2018
Number of pages: 8 Posted: 05 Dec 2019
Jacob S. Sherkow, Patricia J. Zettler and Henry T. Greely
Harvard University, Ohio State University (OSU) - Michael E. Moritz College of Law and Stanford Law School
Downloads 7 (642,091)

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Gene Therapy, CRISPR, CAR-T, FDA, Law

40.

Fortune and Hindsight: Gene Patents’ Muted Effect on Medical Practice

British Medical Bulletin, 2018, Vol. 127, pp. 37–45
Number of pages: 9 Posted: 27 Dec 2019
Jacob S. Sherkow and Ryan Abbott
Harvard University and University of Surrey School of Law
Downloads 5 (656,148)

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medicine, genetics, patents, clinical, diagnostics

41.

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

Frontiers in Immunology, 2019, Vol. 10, art. 435
Number of pages: 13 Posted: 09 Dec 2019
Lund University, National Health Laboratory Services (NHLS) - Centre for HIV and STIs, Karolinska Institutet - Department of Microbiology, Tumor and Cell Biology (MTC), University of London - Birkbeck College, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH) - German Cancer Research Center (DKFZ), Università degli Studi di Genova, Lund University, BISC Global Inc., Garvan Institute of Medical Research, Fred Hutchinson Cancer Research Center, Government of the United States of America - Vaccine Research Center, Simon Fraser University (SFU), Simon Fraser University (SFU), Simon Fraser University (SFU), Independent, University of Oslo, Bar Ilan University, Yale University, University of Texas at Dallas - Southwestern Medical Center, Harvard University, Université de Montpellier, Université de Montpellier, Alfred Hospital, University of Louisville and University of New South Wales (UNSW)
Downloads 1 (692,387)

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immunoglobulin, allelic variation, inference, AIRR-seq, IGHV, V(D)J rearrangement

42.

Differential Requirements for Mcm Proteins in DNA Replication in Drosophila S2 Cells

PLoS One, Vol. 2, e833, 2007
Number of pages: 9 Posted: 05 Dec 2019
NHS Foundation Trust - St. Georges University Hospitals, Kyoto Institute of Technology, Edinburgh Napier University, Harvard University, Kyoto Institute of Technology, University of Edinburgh - Centre for Cardiovascular Science and NHS Foundation Trust - St. Georges University Hospitals
Downloads 1 (692,387)

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MCM, drosophila, PRC, replication, DNA, S2

43.

The CRISPR Patent Landscape: Past, Present, and Future

CRISPR Journal, Vol. 1, pp. 5–9, 2018
Posted: 23 Dec 2019
Jacob S. Sherkow
Harvard University

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CRISPR, Patent, Landscape, Genome Editing, CVC, Broad, Commercial, Licenses, Surrogate

44.

The CRISPR-Cas9 Patent Appeal: Where Do We Go From Here?

CRISPR Journal, Vol. 1, pp. 309–311, 2018
Posted: 20 Dec 2019
Jacob S. Sherkow
Harvard University

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CRISPR, Patent, Cvc, Broad, Appeal

45.

Controlling CRISPR Through Law: Legal Regimes as Precautionary Principles

CRISPR Journal, 2019, Vol. 2, pp. 299–303
Posted: 27 Nov 2019
Jacob S. Sherkow
Harvard University

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CRISPR, bioethics, biotechnology, ethics, precautionary principle, law, regulation, tort, patents, policy

46.

Patent Pools for CRISPR Technology — Response

Science, Vol. 355(6331), pp. 1274-1275 (2017)
Posted: 28 Jun 2017 Last Revised: 13 Nov 2019
Jorge L. Contreras and Jacob S. Sherkow
University of Utah - S.J. Quinney College of Law and Harvard University

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crispr, licensing, biotechnology, intellectual property, patents, pools, mpegla, genetics