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Afshan McCarthy

The Francis Crick Institute

1 Midland Road

London, NW1 1AT

United Kingdom

  • The Francis Crick Institute

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Scholarly Papers (1)

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Human Naïve-to-Primed Epiblast Transition Requires Suppression of Extraembryonic Competence by SALL2

Number of pages: 79 Posted: 20 Apr 2026
Qiulin Huang, Desislava Staneva, Afshan McCarthy, Claire S. Simon, Thomas E. Bartlett, Peter J. Rugg-Gunn, Robin   Lovell Badge, Kathy K. Niakan and Sneak Peek Administrator
University of Cambridge, University of Cambridge, The Francis Crick Institute, University of Cambridge, University College London, University of Cambridge, The Francis Crick Institute, University of Cambridge and Independent
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Abstract:

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Human pluripotency, Pluripotent stem cells, Epiblast, SALL2, Naive-to-Primed transition, Early human development, Extraembryonic differentiation, Trophectoderm, Primitive endoderm, WNT signaling, Capacitation