Fondazione IRCCS Istituto Nazionale dei Tumori - Head and Neck Medical Oncology Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Campania Luigi Vanvitelli, Ospedale Santa Chiara - Azienda Ospedaliero Universitaria Pisana, Fondazione Policlinico Universitario A. Gemelli IRCCS - COU of Dermatology, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Trieste, Fondazione IRCCS Istituto Nazionale dei Tumori, IRCCS Ospedale Policlinico San Martino - Department of Medical Oncology, IRCCS Humanitas Research Hospital, University of Brescia, University of Trieste and University of Brescia - Medical Oncology Unit