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Cole Kappel

University of California, Irvine

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Scholarly Papers (1)

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Leveraging Endogenous Resilience Mechanisms in Retrosplenial Cortex to Slow Progression of Alzheimer's Disease

Number of pages: 88 Posted: 02 May 2026
Pieter Derdeyn, Lingxuan Chen, Haoshan Chen, Megan Nguyen, Jessica Moore, Cole Kappel, Yanjun Sun, Erick Ho, Desiree Macchia, Nicolas Krohn, Ghalia Azouz, Jose Vasquez, Yuan Li, Guilian Tian, Max Lin, Ladan Bigdeli, Marjan Rashidi, Katrina Bartas, Zhoule Zhu, Elizabeth R. Chrastil, Kevin Thomas Beier and Sneak Peek Administrator
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Endogenous resilience mechanisms, retrosplenial cortex, voltage-gated potassium channels, carnosic acid, KCNQ opener, hyperexcitability, hyperactivity, rabies tracing, miniscope, chemogenetic behavioral modulation, mathematical modeling, plaques, slice electrophysiology, 5xFAD, APPNL-G-F, P301S::E4, tauopathy, ApoE4.