affiliation not provided to SSRN, affiliation not provided to SSRN, Vancouver Coastal Health Research Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of British Columbia (UBC), University of British Columbia (UBC) - Vancouver Stroke Program, affiliation not provided to SSRN, University of British Columbia (UBC) - Djavad Mowafaghian Centre for Brain Health, University of British Columbia (UBC) - Djavad Mowafaghian Centre for Brain Health, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Vancouver General Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN