Government of the United States of America - Lymphocyte Cell Biology Section, Kyoto University, Kyorin University School of Medicine - Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University - Department of Gastroenterology and Hepatology, Kitasato University - Center for Advanced IBD Research and Treatment, Tokyo Women's Medical University, Hyogo Medical University, Hyogo Medical University, Jikei University, Sapporo Kosei General Hospital - IBD Center, Yokkaichi Hazu Medical Center, Kyorin University, Kyorin University, Johns Hopkins University and Kitasato University - Center for Advanced IBD Research and Treatment