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Mengfan Zhang

affiliation not provided to SSRN

  • affiliation not provided to SSRN

SCHOLARLY PAPERS

2

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12

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Scholarly Papers (2)

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1.

Quality by Design-Based Continuous Manufacturing of Hot-Melt Extruded Orodispersible Films: Online NIR-MSPC Monitoring

Number of pages: 26 Posted: 13 Jun 2026
Xianfu Li, Mengfan Zhang, Ziyao Liu, Yisen Wang, Lian Li, Hui Zhang, Nan Liu, Zengming Wang, Lili Jin and Aiping Zheng
Beijing Institute of Pharmacology and Toxicology, affiliation not provided to SSRN, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Shandong University - School of Pharmaceutical Sciences, Beijing Institute of Pharmacology and Toxicology, Beijing Institute of Pharmacology and Toxicology, Beijing Institute of Pharmacology and Toxicology, Yanbian University and Beijing Institute of Pharmacology and Toxicology
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Hot-melt extrusion, Orodispersible films, Brexpiprazole, Multivariate statistical process control, Process analytical technology.

2.

In-line near-infrared spectroscopy and deployment-oriented machine learning for monitoring hot-melt extruded orodispersible films continuous production

Number of pages: 31 Posted: 24 Jul 2026
Xianfu Li, Mengfan Zhang, Lidan Qiang, Ziyao Liu, Yisen Wang, Siyi Shuai, Zengming Wang, Hui Zhang, Lian Li, Lili Jin and Aiping Zheng
Beijing Institute of Pharmacology and Toxicology, affiliation not provided to SSRN, affiliation not provided to SSRN, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Beijing Institute of Pharmacology and Toxicology, Beijing Institute of Pharmacology and Toxicology, Shandong University - School of Pharmaceutical Sciences, Yanbian University and Beijing Institute of Pharmacology and Toxicology
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Abstract:

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Near-Infrared Spectroscopy, hot-melt extrusion, orodispersible film, process analytical technology, Chemometrics, in-line monitoring