Stanford University, affiliation not provided to SSRN, Massachusetts General Brigham - Harvard Medical School Institute for Technology Assessment, Tufts University - Tufts Medical Center, Columbia University College of Physicians and Surgeons, Columbia University College of Physicians and Surgeons, Harvard University - Dana-Farber Cancer Institute, Harvard University - Massachusetts General Hospital, Harvard University - Massachusetts General Hospital, Tufts University - Tufts Medical Center and affiliation not provided to SSRN