default author photo

Sheyne Choi

Institute of Cancer Research (ICR)

SCHOLARLY PAPERS

1

DOWNLOADS

11

TOTAL CITATIONS

0

Scholarly Papers (1)

1.

Mutational and Functional Heterogeneity of Homology-Directed Repair Deficiency and Clinical Implications

Number of pages: 39 Posted: 16 Jun 2026
University of Cambridge, University of Cambridge, Institute of Cancer Research (ICR), Institute of Cancer Research (ICR), National Institutes of Health, Bethesda, Institute of Cancer Research (ICR), Institute of Cancer Research (ICR), University of Cambridge, University of Cambridge, University of Cambridge, University of Oxford, University of Cambridge, University of Cambridge, University of Cambridge, Memorial Sloan Kettering Cancer Center, University of Cambridge, University of Cambridge, University of Cambridge, University of Cambridge, Institute of Cancer Research (ICR), University of Oxford, Memorial Sloan Kettering Cancer Center - Developmental Biology Program, Institute of Cancer Research (ICR), National Institutes of Health, Bethesda, Institute of Cancer Research (ICR), University of Cambridge and Independent
Downloads 11

Abstract:

Loading...

Mutational signatures, CRISPR screen, homologous recombination repair, synthetic lethality, isogenic cell lines, PARP inhibitor resistance, therapeutic vulnerability, BRCA, DNA repair, mutagenesis