National Heart Centre Singapore, National University of Singapore (NUS) - Department of Cardiology, University of Glasgow, University Hospital Würzburg, Linkoping University - Linköping University Hospital, University Hospital Würzburg, Alexandria University, Argentine Catholic University, M-Ghadanfar Consulting Life Sciences, Novartis Institutes for Biomedical Research, Cambridge - Novartis Pharma AG, University of Cyprus, - 2nd Department of Cardiology, University of Bergen, National Heart Centre Singapore, University of Amsterdam - Amsterdam University Medical Centers and National Heart Centre Singapore