McMaster University, McMaster University, McMaster University, Princess Margaret Hospital, affiliation not provided to SSRN, University of Padua, McMaster University - Division of Orthopaedic Surgery, McMaster University - Department of Anesthesia, McMaster University, McMaster University - Department of Medicine, McMaster University, McMaster University, Princess Margaret Hospital, University of Michigan, McMaster University, McMaster University, McMaster University, McMaster University, McMaster University, McMaster University, McMaster University, McMaster University and McMaster University