University of Glasgow - Institute of Cardiovascular and Medical Sciences, University of Glasgow - Institute of Cardiovascular and Medical Sciences, University of Glasgow - Institute of Cardiovascular and Medical Sciences, University Hospitals Birmingham NHS Foundation Trust, Mabgenex, Canon Medical Research Europe Ltd, Medical University of Gdańsk - Department of Hypertension and Diabetology, Medical University of Gdańsk - Department of Hypertension and Diabetology, Medical University of Gdańsk - Department of Hypertension and Diabetology, Medical University of Gdańsk - Department of Hypertension and Diabetology, Medical University of Gdańsk - Department of Hypertension and Diabetology, Deakin University, Medical University of Gdańsk - Department of Hypertension and Diabetology, University Hospitals Birmingham NHS Foundation Trust, University of Glasgow - Institute of Cardiovascular and Medical Sciences, University of Pittsburgh - Department of Biomedical Informatics, University of Glasgow - Institute of Cardiovascular and Medical Sciences and University of Glasgow - Institute of Cardiovascular and Medical Sciences