University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), German Cancer Research Center (DKFZ), University of Edinburgh - School of Physics and Astronomy, Institute of Molecular Biology (IMB), Institute of Molecular Biology (IMB), University of Cologne - Cologne Center for Genomics (CCG), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), RWTH Aachen University - Helmholtz Institute for Biomedical Engineering, University of Cologne - Center for Integrated Oncology (CIO), RWTH Aachen University - Interdisciplinary Centre for Clinical Research (IZKF), RWTH Aachen University - Interdisciplinary Centre for Clinical Research (IZKF), University of Cologne - Center for Molecular Medicine Cologne (CMMC), RWTH Aachen University - Helmholtz Institute for Biomedical Engineering, Institute of Molecular Biology (IMB), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Edinburgh - School of Physics and Astronomy, German Cancer Research Center (DKFZ) and University of Göttingen - Translational Epigenetics Group