Zhengzhou University, Emory University - Department of Pathology and Laboratory Medicine, Emory University - Department of Pathology and Laboratory Medicine, Emory University - School of Medicine, Emory University - Department of Pathology and Laboratory Medicine, Emory University - Department of Anesthesiology, Michigan State University - Department of Translational Science and Molecular Medicine, Michigan State University - Department of Translational Science and Molecular Medicine, Government of the United States of America - Mouse Cancer Genetics Program, Capital Medical University - Innovation Center for Neurological Disorders, Huazhong University of Science and Technology - Department of Pathophysiology and Emory University - Department of Pathology and Laboratory Medicine