University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Cologne - Center for Molecular Medicine Cologne (CMMC), University of Copenhagen - Biotech Research and Innovation Centre (BRIC), Erasmus University Rotterdam (EUR) - Erasmus Medical Center (MC), University of Cologne - Center for Physiology and Pathophysiology, Heinrich Heine University Dusseldorf - Duesseldorf Institute for Competition Economics (DICE), University of Cologne - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Southampton - Department of Human Genetics and Genomic Medicine, University of Exeter - Institute of Biomedical and Clinical Science and University of Cologne - Center for Molecular Medicine Cologne (CMMC)