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Francesco Iorio

Wellcome Genome Campus - Wellcome Sanger Institute

Hinxton, Saffron Walden

Cambridge, England CB10 1SA

United Kingdom

Human Technopole

  • Wellcome Genome Campus - Wellcome Sanger Institute

SCHOLARLY PAPERS

4

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125

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0

Scholarly Papers (4)

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1.

CellMinerCDB for Integrative Genomics and Pharmacogenomics Analyses of Cancer Cell Lines

Number of pages: 31 Posted: 08 Jun 2018
Vinodh Rajapakse, Augustin Luna, Mihoko Yamade, Lisa Loman, Sudhir Varma, Margot Sunshine, Francesco Iorio, Fabricio G. Sousa, Fathi Elloumi, Mirit I. Aladjem, Anish Thomas, Chris Sander, Kurt Kohn, Cyril H. Benes, Mathew Garnett, William Reinhold and Yves Pommier
National Institutes of Health - Developmental Therapeutics Branch, Dana Farber Cancer Institute - cBio Center, Hamamatsu University - First Department of Medicine, Government of the United States of America - Developmental Therapeutics Branch, National Institutes of Health - Developmental Therapeutics Branch, Government of the United States of America - Developmental Therapeutics Branch, Wellcome Genome Campus - Wellcome Sanger Institute, Universidade Federal de Mato Grosso - Centro de Estudos em Células Tronco, Terapia Celular e Genética Toxicológica, Government of the United States of America - Developmental Therapeutics Branch, National Institutes of Health - Developmental Therapeutics Branch, National Institutes of Health - Developmental Therapeutics Branch, Dana Farber Cancer Institute - cBio Center, National Institutes of Health - Developmental Therapeutics Branch, Harvard University - Cancer Center, Wellcome Genome Campus - Wellcome Trust Sanger Institute, National Institutes of Health - Developmental Therapeutics Branch and Center for Cancer Research, National Cancer Institute, NIH, Bethesda
Downloads 42 (1,157,785)

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2.

CRISPRcleanR WebApp: An Interactive Web Application for Processing Genome-Wide Pooled CRISPR-Cas9 Viability Screen

Number of pages: 38 Posted: 11 Apr 2022
Alessandro Vinceti, Riccardo Roberto De Lucia, Paolo Cremaschi, Umberto Perron, Emre Karakoc, Luca Mauri, Carlos Fernandez, Krzysztof Henryk Kluczynski, Daniel Stephen Anderson and Francesco Iorio
Human Technopole, Human Technopole, Human Technopole, Human Technopole, Wellcome Genome Campus - Wellcome Sanger Institute, Human Technopole, Human Technopole, Human Technopole, Human Technopole and Wellcome Genome Campus - Wellcome Sanger Institute
Downloads 33 (1,277,121)

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CRISPR-Cas9 screens, Copy number, Bias correction, Cancer dependency, Unsupervised analysis, Web-application

3.

Identification of Intrinsic Drug Resistance and Their Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens

Number of pages: 34 Posted: 06 Apr 2020
Iñigo Ayestaran, Ben Sidders, Jonathan Dry, Andreas Bender, Ultan McDermott, Francesco Iorio and Michael Patrick Menden
Helmholtz Zentrum München - Institute of Computational Biology, AstraZeneca - Translational Medicine, Research and Early Development, AstraZeneca, University of Cambridge - Centre for Molecular Informatics, AstraZeneca Pharmaceuticals, Wellcome Genome Campus - Wellcome Sanger Institute and Helmholtz Zentrum München - Institute of Computational Biology
Downloads 32 (1,290,922)

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Precision Medicine, Cancer, Drug Resistance, Early Drug Discovery, Biostatistics, Biomarker Discovery, Drug High-Throughput Screens, Cancer Cell Lines, CRISPR, Drug Combinations

4.

Reduced Gene Templates for Supervised Analysis of Scale-Limited CRISPR-Cas9 Fitness Screens

Number of pages: 44 Posted: 04 Mar 2022
Alessandro Vinceti, Umberto Perron, Lucia Trastulla and Francesco Iorio
Wellcome Genome Campus - Wellcome Trust Sanger Institute, Human Technopole, Wellcome Genome Campus - Wellcome Trust Sanger Institute and Wellcome Genome Campus - Wellcome Sanger Institute
Downloads 18 (1,470,786)

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CRISPR-Cas9 screens, cancer dependency, reference genes, scale-limited screens, supervised analysis