University of Milano Bicocca - Centro Ricerca M. Tettamanti, Paediatrics, South Hospital, Università degli Studi di Milano-Bicocca - Department of Pediatrics, University of Kiel - University Medical Center, Dr Children's Hospital Roberto del Río - Chilean National Pediatric Oncology Group (PINDA), Lund University - Department of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Université Paris VII Denis Diderot - Robert Debré Hospital, Great Ormond Street Hospital - Department of Haematology, Università degli Studi di Milano-Bicocca - Department of Pediatrics, Dr Children's Hospital Roberto del Río - Chilean National Pediatric Oncology Group (PINDA), The Chinese University of Hong Kong (CUHK), Università degli Studi di Milano-Bicocca - Tettamanti Research Center, Université Paris VII Denis Diderot - Robert Debré Hospital, University of Giessen - Department Pediatric Hematology and Oncology, Università degli Studi di Milano-Bicocca - Department of Pediatrics, The University of Manchester - Division of Cancer Sciences, University of Kiel - University Medical Center and University of Milan-Bicocca - Bicocca Center of Bioinformatics, Biostatistics and Bioimaging (B4 Center)