Alexander J. Mentzer

University of Oxford - Wellcome Centre for Human Genetics

University of Oxford - Li Ka Shing Centre for Health Information and Discovery

Oxford , OX3 7FZ

United Kingdom

SCHOLARLY PAPERS

10

DOWNLOADS

464

TOTAL CITATIONS

26

Scholarly Papers (10)

1.

Discovery and Validation of a 3-Gene Transcriptional Signature to Distinguish COVID-19 and Other Viral Infections from Bacterial Sepsis in Adults; A Case-Control then Observational Cohort Study

Number of pages: 38 Posted: 02 Feb 2021
Imperial College London, Imperial College London - Section of Paediatric Infectious Disease, Imperial College London, Imperial College London, Imperial College London, Imperial College London, University College London, Imperial College London, Imperial College London - Imperial College Healthcare NHS Trust, Department of Infectious Disease, Imperial College London, Imperial College London - Institute of Reproductive and Developmental Biology, Imperial College London, Imperial College London, Imperial College London, Department of Infectious Disease, Imperial College London, Imperial College London - Section of Paediatric Infectious Disease, Imperial College London, Imperial College London, University College London - Institute for Health Informatics, University of Oxford - Wellcome Centre for Human Genetics, Department of Infectious Disease, Imperial College London, Imperial College London - Department of Infectious Disease, University College London - Division of Infection and Immunity and Imperial College London - Department of Medicine
Downloads 130 (449,071)
Citation 1

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2.

Vitamin D Deficiency in Young African Children

Number of pages: 26 Posted: 30 Dec 2020
Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University of Oxford - Wellcome Centre for Human Genetics, London School of Hygiene & Tropical Medicine, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University of the Witwatersrand - South African Medical Research Council Vaccines and Infectious Diseases Analytical Research Unit, Groupe de Recherche Action en Santé (GRAS), Groupe de Recherche Action en Santé (GRAS), Groupe de Recherche Action en Santé (GRAS), University College London - Institute for Global Health, Oxford University Hospitals - Department of Clinical Biochemistry, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University of the Witwatersrand - South African Medical Research Council /Wits Developmental Pathways for Health Research Unit,, London School of Hygiene and Tropical Medicine - Department of Clinical Research, National Institutes of Health - Centre for Research on Genomics and Global Health, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme and Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme
Downloads 66 (692,592)
Citation 1

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Vitamin D; 25-hydroxyvitamin D; vitamin D deficiency; Africa; children; inflammation; malaria; age; sex; nutritional status; BRINDA

3.

­­­The Antigenic Anatomy of SARS-CoV-2 Receptor Binding Domain

Number of pages: 87 Posted: 23 Dec 2020
University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, Diamond Light Source Ltd - Harwell Science & Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University School of Medicine - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology, University of Oxford - MRC Human Immunology Unit, University of Oxford - Sir William Dunn School of Pathology, University of Oxford - Sir William Dunn School of Pathology, Public Health England - National Infection Service, Public Health England - National Infection Service, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Worthing Hospital, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Kent - Viral Pseudotype Unit, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - MRC Human Immunology Unit, Chang Gung University - Research Center for Emerging Viral Infections, University of Oxford - Division of Structural Biology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Washington University School of Medicine - Department of Medicine, University of Oxford - Division of Structural Biology, Weizmann Institute of Science - Department of Biomolecular Sciences and University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI)
Downloads 53 (768,794)
Citation 7

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SARS-CoV-2, antibody, germline, V-gene, receptor-binding-domain, spike, neutralisation, protection, glycosylation, valency

4.

Estimating the Hidden Burden of Iron Deficiency Among African Children

Number of pages: 30 Posted: 17 May 2019
Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University of Oxford - Wellcome Centre for Human Genetics, London School of Hygiene & Tropical Medicine, Oxford University Hospitals - Department of Clinical Biochemistry, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University College London - Institute for Global Health, University of the Witwatersrand - Faculty of Health Sciences, Groupe de Recherche Action en Santé (GRAS), Groupe de Recherche Action en Santé (GRAS), Groupe de Recherche Action en Santé (GRAS), Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of Oxford - The Jenner Institute, London School of Hygiene & Tropical Medicine - Medical Research Council Unit The Gambia, Emory University, London School of Hygiene & Tropical Medicine, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme and Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme
Downloads 53 (768,794)
Citation 2

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Iron deficiency; Ferritin; Transferrin saturation; Inflammation; Malaria; Malnutrition; African children

5.

Fatal COVID-19 Outcomes are Associated with an Antibody Response Targeting Epitopes Shared with Endemic Coronaviruses

Number of pages: 32 Posted: 02 Jun 2021
University of Oxford, University of Oxford, University of Oxford, St. George’s University of London - Institute of Infection & Immunity, University of Oxford, University of Oxford, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - The Jenner Institute, University of Oxford, St. George's University - Intensive Care Medicine, University of Cambridge, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Oxford Vaccine Group, University of Oxford, Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College, London, University of Oxford, University of Oxford, University of Oxford, St. George's University - General Intensive Care, University of Oxford, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Nuffield Department of Medicine, St George's, University of London, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford, University of Oxford, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford, University of Oxford - Wellcome Centre for Human Genetics, University of Kent - Viral Pseudotype Unit, Meso-­‐Scale Diagnostics, University of Oxford - Wellcome Centre for Human Genetics, Guy's and St Thomas' NHS Foundation Trust - Intensive Care Medicine, Independent, Independent, University of Oxford - Nuffield Department of Medicine, University of Oxford - The Jenner Institute, University of Edinburgh - Roslin Institute, University of Liverpool - Health Protection Research Unit in Emerging and Zoonotic Infections, Imperial College London - National Heart and Lung Institute (NHLI), Independent, Tel Aviv University, Leidos Inc., University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford, affiliation not provided to SSRN, Oxford University Hospitals NHS Foundation Trust, Mahidol University - Mahidol-Oxford Tropical Medicine Research Unit, University of Oxford - Department of Zoology, University of Oxford - Peter Medawar Building for Pathogen Research, St. George’s University of London - Institute of Infection & Immunity, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology and University of Oxford - Peter Medawar Building for Pathogen Research
Downloads 52 (775,291)
Citation 4

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6.

The Impact of Viral Mutations on Recognition by SARS-CoV-2 Specific T-Cells

Number of pages: 32 Posted: 12 May 2021
University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Sheffield - Department of Infection, Immunity and Cardiovascular Disease, University of Oxford - Wellcome Centre for Human Genetics, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Sheffield Biomedical Research Centre, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Mahidol University - Mahidol-Oxford Tropical Medicine Research Unit, Independent, University College London - Division of Infection and Immunity, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease and University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI)
Downloads 30 (954,538)
Citation 7

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7.

Joint Sequencing of Human and Pathogen Genomes Reveals the Genetics of Pneumococcal Meningitis

Number of pages: 74 Posted: 16 Aug 2018 Last Revised: 24 Sep 2018
New York University (NYU) - Department of Microbiology, University of Amsterdam - Department of Neurology, University of Amsterdam - Department of Neurology, Wellcome Genome Campus - Infection Genomics, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, Imperial College London - Department of Infectious Disease, Wellcome Genome Campus - Infection Genomics, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, Wellcome Genome Campus - Infection Genomics, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, Utrecht University - Department of Pediatric Immunology and Infectious Diseases, University of Amsterdam - Department of Biostatistics, Utrecht University - Department of Neurology, Utrecht University - Department of Neurology, Utrecht University - Department of Neurology, Statens Serums Institut - Department of Microbiological Surveillance and Research, University of Copenhagen - Department of Infectious Diseases, Wageningen University and Research (WUR) - Department of Human Nutrition, University of Amsterdam - Amsterdam Public Health Research Institute, University of Amsterdam - Amsterdam Public Health Research Institute, Bispebjerg and Frederiksberg Hospitals - Center for Clinical Research and Disease Prevention, University of Copenhagen - Section of Metabolic Genetics, University of Southern Denmark - Institute of Clinical Research, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of the Witwatersrand, University of the Witwatersrand, New York University (NYU) - Department of Microbiology, Wellcome Genome Campus - Infection Genomics, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of Copenhagen - Department of Infectious Diseases, National Health Laboratory Services (NHLS) - Centre for Respiratory Diseases and Meningitis, University of Amsterdam - Netherlands Reference Laboratory for Bacterial Meningitis, University of Amsterdam - Department of Neurology, Wellcome Genome Campus - Infection Genomics, Wellcome Sanger Institute - Parasites and Microbes and University of Amsterdam - Department of Neurology
Downloads 26 (995,952)

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8.

Evaluation of T Cell Responses to Naturally Processed Variant SARS-CoV-2 Spike Antigens in Individuals Following Infection or Vaccination

Number of pages: 46 Posted: 30 Jan 2023
University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Cambridge - Department of Pathology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Cambridge - Department of Pathology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford - MRC Weatherall Institute of Molecular Medicine, University of Oxford, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Cambridge - Department of Pathology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI) and University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI)
Downloads 22 (1,040,673)

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SARS-CoV-2, variants of concern, spike protein, T cell, antigen processing and presentation, immune escape, recombinant vaccinia virus, ChAdOx1 nCoV-19

9.

Evolution of Long-Term Hybrid Immunity in Healthcare Workers after Different Covid-19 Vaccination Regimens: A Longitudinal Observational Cohort Study

Number of pages: 56 Posted: 08 Aug 2022
University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Oxford Vaccine Group, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Birmingham - Clinical Immunology Service, University of Birmingham - Institute of Cancer and Genomic Science, University of Oxford - Pandemic Sciences Institute, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, NHS Foundation Trust - Liverpool University Hospitals NHS Foundation Trust (LUH), Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Dept Infection, Immunity & Cardiovascular Disease, University of Sheffield, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Dept of Infectious Diseases & Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Newcastle Upon Tyne Hospitals NHS Foundation Trust - Department of Infection and Tropical Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Birmingham - Institute of Immunology and Immunotherapy, University of Cambridge - MRC Toxicology Unit, University of Cambridge - MRC Toxicology Unit, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation Trust, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Oxford Vaccine Group, University of Oxford - Peter Medawar Building for Pathogen Research, Sheffield Teaching Hospitals NHS Foundation Trust, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Oxford - Oxford Vaccine Group, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Cambridge - MRC Toxicology Unit, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, Public Health England Colindale, Newcastle University - Translational and Clinical Research Institute, University of Birmingham - Institute of Cancer and Genomic Sciences, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Oxford - Nuffield Department of Clinical Medicine, Mahidol University - Mahidol-Oxford Tropical Medicine Research Unit, University of Liverpool - NIHR Health Protection Research Unit for Emerging and Zoonotic Infection and Independent
Downloads 18 (1,088,817)
Citation 4

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SARS-CoV-2, COVID-19, COVID vaccine, T cells, antibody, immunity

10.

Large Clones of Pre-Existing T Cells Drive Early Immunity Against SARS-COV-2 and LCMV Infection

Number of pages: 45 Posted: 15 Feb 2023
University College London - Division of Infection and Immunity, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University College London - UCL Genetics Institute, Weizmann Institute of Science - Department of Systems Immunology, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University College London - Division of Infection and Immunity, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University College London - UCL Genetics Institute, Weizmann Institute of Science - Department of Systems Immunology, Weizmann Institute of Science - Department of Systems Immunology, Queen Mary University of London - Blizard Institute, Queen Mary University of London - Blizard Institute, Queen Mary University of London - Blizard Institute, UK Health Security Agency, UK Health Security Agency - Rare & Imported Pathogens Laboratory, Imperial College London - Department of Immunology and Inflammation, Imperial College London - Department of Infectious Disease, University College London - Division of Infection and Immunity, Queen Mary University of London - Blizard Institute, University College London - Institute of Cardiovascular Science, University College London - Institute of Cardiovascular Science, University College London - Institute of Cardiovascular Science, Independent, University College London - Division of Infection and Immunity and University College London - Division of Infection and Immunity
Downloads 14 (1,138,803)

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SARS-CoV-2, T cell receptor, naive repertoire, LCMV