Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Tsinghua University - MOE Key Laboratory of Protein Sciences, Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Shanghai Jiao Tong University (SJTU) - School of Biomedical Engineering, Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Chinese Academy of Sciences (CAS) - Laboratory of Protein and Peptide Pharmaceuticals, Fujian Agriculture and Forestry University - School of Life Science, Tsinghua University - MOE Key Laboratory of Protein Sciences, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Shanghai Jiao Tong University (SJTU) - Instrumental Analysis Center, Shanghai Jiao Tong University (SJTU) - Instrumental Analysis Center and Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB)