Ruth Nussinov

National Institutes of Health (NIH) - National Cancer Institute at Frederick

Frederick, MD 21702-1201

United States

Tel Aviv University - Department of Human Molecular Genetics and Biochemistry

Tel Aviv, 69978

Israel

SCHOLARLY PAPERS

3

DOWNLOADS

34

CITATIONS

0

Scholarly Papers (3)

1.

Individualized Genetic Network Analysis Reveals New Therapeutic Vulnerabilities in Cancer

Number of pages: 56 Posted: 03 Oct 2018
Hangzhou Normal University - Alibaba Research Center for Complexity Sciences, Columbia University - Department of Systems Biology, Hangzhou Normal University - Alibaba Research Center for Complexity Sciences, Cleveland Clinic - Genomic Medicine Institute, National Institutes of Health (NIH) - National Cancer Institute at Frederick, Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute and Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute
Downloads 22 (503,511)

Abstract:

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tumor vulnerability; genetic interaction; pharmacogenomics; somatic mutations; network analysis; personalized cancer medicine

2.

Target Identification Among Known Drugs by Deep Learning from Heterogeneous Networks

CELL-CHEMICAL-BIOLOGY-D-19-00154
Number of pages: 100 Posted: 13 May 2019
Xiamen University - Department of Computer Science, Xiamen University - Department of Computer Science, East China Normal University (ECNU) - Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China University of Science and Technology (ECUST), School of Pharmacy, Shanghai Key Laboratory of New Drug Design, East China University of Science and Technology (ECUST), School of Pharmacy, Shanghai Key Laboratory of New Drug Design, Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute, Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute, China Pharmaceutical University - Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University - Key Laboratory of Drug Quality Control and Pharmacovigilance, Guangzhou University of Chinese Medicine - Institute of Clinical Pharmacology, East China Normal University (ECNU) - Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, Cleveland Clinic - Department of Neurosciences, Ohio State University (OSU) - Department of Biomedical Informatics, National Institutes of Health (NIH) - National Cancer Institute at Frederick, Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute, Harvard University, Harvard Medical School, Brigham and Women's Hospital, Department of Medicine and Cleveland Clinic, Lerner Research Institute, Genomic Medicine Institute
Downloads 9 (580,404)

Abstract:

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drug-target network, deep learning, heterogeneous networks, topotecan, ROR-γt, multiple sclerosis

3.

The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin

STRUCTURE-D-19-00185
Number of pages: 59 Posted: 11 Jul 2019
National Laboratory for Cancer Research, University of Illinois at Chicago, Northeastern University, Northeastern University, Northeastern University - Department of Chemistry and Chemical Biology, University of Illinois at Chicago and National Institutes of Health (NIH) - National Cancer Institute at Frederick
Downloads 3 (620,718)

Abstract:

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post-translational modifications, farnesylation and methylation, phosphatidylinositol, PIP2, NMR, MD simulation, SAXS, PI3K