Huacheng Luo

Penn State College of Medicine

700 HMC Crescent Road Hershey

Hershey, PA 17033

United States

SCHOLARLY PAPERS

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CITATIONS

1

Ideas:
“  1. HOTTIP lncRNA reprograms chromatin structure and drives leukemic transcription profile in AML.2. HOTTIP directly binds and regulates genes important for hematopoiesis and leukemogenesis.3. Loss of HOTTIP lncRNA attenuates AML progression by impairing leukemic transcription program.4. Hottip overexpression perturbs HSC self-renewal and differentiation leading to AML-like disease in mice.  ”

Scholarly Papers (1)

1.

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-Like Disease in Mice

Number of pages: 61 Posted: 31 Oct 2018
Penn State College of Medicine, University of Miami Miller School of Medicine, Xiamen University, University of Florida, University of Miami - Department of Biochemistry & Molecular Biology, Baylor University - Department of Molecular and Cellular Biology, Penn State University College of Medicine, Xiamen University, Baylor University - Department of Molecular and Cellular Biology, University of Miami, University of Florida, University of Florida, University of Miami Miller School of Medicine and Penn State University College of Medicine
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Citation 2

Abstract:

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HOTTIP lncRNA, chromatin domain, HOX gene regulation, enhancer/promoter accessibility, transcription regu