Alain Townsend

University of Oxford - MRC Human Immunology Unit

Oxford, Oxfordshire, England

United Kingdom

SCHOLARLY PAPERS

3

DOWNLOADS

73

SSRN CITATIONS

9

CROSSREF CITATIONS

0

Scholarly Papers (3)

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 58 Posted: 01 Jun 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and University of Oxford - Division of Structural Biology
Downloads 22 (619,738)
Citation 3

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SARS-CoV-2, Spike, X-ray crystallography, Cryo-EM, Neutralisation, Monoclonal antibody, neutralising monoclonal antibody, COVID-19

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 53 Posted: 12 May 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and University of Oxford - Division of Structural Biology
Downloads 15 (672,605)

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Covid-19, SARS-CoV-2, Antibody Structure, Spike, Receptor Binding Domain, Neutralisation, Therapeutic Antibody, Crystallography, Cryo-EM, virus structure

2.

­­­The Antigenic Anatomy of SARS-CoV-2 Receptor Binding Domain

Number of pages: 87 Posted: 23 Dec 2020
University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology, University of Oxford - MRC Human Immunology Unit, University of Oxford - Sir William Dunn School of Pathology, University of Oxford - Sir William Dunn School of Pathology, Public Health England - National Infection Service, Public Health England - National Infection Service, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Worthing Hospital, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Kent - Viral Pseudotype Unit, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - MRC Human Immunology Unit, Chang Gung University - Research Center for Emerging Viral Infections, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and University of Oxford - Wellcome Centre for Human Genetics
Downloads 31 (545,496)

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SARS-CoV-2, antibody, germline, V-gene, receptor-binding-domain, spike, neutralisation, protection, glycosylation, valency

3.

Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans

Number of pages: 62 Posted: 24 Oct 2018
University of Oxford - MRC Human Immunology Unit, University of Oxford - The Jenner Institute, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, UCB - UCB Pharma, UK, UCB - UCB Pharma, UK, UCB - UCB Pharma, UK, University of Oxford - The Jenner Institute, University of Oxford - The Jenner Institute, University of Oxford - The Jenner Institute, University of Oxford - The Jenner Institute, Government of the United Kingdom - Public Health England, University of Oxford - The Jenner Institute, Government of the United Kingdom - Public Health England, Government of the United Kingdom - Public Health England, Government of the United Kingdom - Public Health England, Public Health England - National Infection Service, Imperial College London, Imperial College London, Chang Gung University - Division of Pediatric Infectious Diseases, Hokkaido University - Division of Global Epidemiology, UCB - UCB Pharma, UK, UCB - UCB Pharma, UK, UCB - UCB Pharma, UK, UCB - UCB Pharma, UK, University of Oxford - The Jenner Institute and University of Oxford - MRC Human Immunology Unit
Downloads 5 (723,582)
Citation 1

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Ebola virus, human monoclonal antibodies, immunotherapy, therapeutic antibodies, guinea pig model, Ebola virus glycoprotein epitopes, E-S-FLU virus, antibody binding kinetics, affinity maturation