Peking University School and Hospital of Stomatology, Central Laboratory and Department of Pathology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology, Xinjiang Medical University - Department of Joint Surgery, Chinese Academy of Sciences (CAS) - Shanghai Institute of Biochemistry and Cell Biology, Peking University, Third Hospital, Department of Orthopedics, Yeshiva University - Department of Genetics, Pediatrics, and Medicine (Cardiology) and University of Massachusetts Worcester - Department of Molecular, Cell and Cancer Biology