Yi Sun

Zhejiang University - Institute of Translational Medicine

China

University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology

1500 E Medical Center Dr.

UH B2C490

Ann Arbor, 48109-5010

United States

SCHOLARLY PAPERS

4

DOWNLOADS

34

SSRN CITATIONS

0

CROSSREF CITATIONS

0

Scholarly Papers (4)

1.

LSD1 Destabilizes FBXW7 Independent of Its Demethylase Activity

Number of pages: 49 Posted: 09 Nov 2018
Zhejiang University - Institute of Translational Medicine, University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology, University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology, Zhejiang University - Institute of Translational Medicine, University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology, Zhejiang University - Institute of Translational Medicine and Zhejiang University - Institute of Translational Medicine
Downloads 14 (600,577)

Abstract:

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Degradation, DNA damage repair, Protein demethylation, Radiation sensitization, SCF E3 ligase, Ubiquitylation

2.

FBXW7 Confers Radiation Survival by Targeting p53 for Degradation

CELL-REPORTS-D-19-02728
Number of pages: 35 Posted: 31 Jul 2019
Zhejiang University - Key Laboratory of Combined Multi-Organ Transplantation, Zhejiang University - Institute of Translational Medicine, Zhejiang University - Institute of Translational Medicine and Zhejiang University - Key Laboratory of Combined Multi-Organ Transplantation
Downloads 9 (634,707)

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FBXW7, p53, E3 ligase, DNA damage, radiosensitivity

3.

The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

CELL-REPORTS-D-20-00547
Number of pages: 55 Posted: 03 Mar 2020
Zhejiang University - Institute of Translational Medicine, Zhejiang University - Institute of Translational Medicine, University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology, Zhejiang University - Institute of Translational Medicine, University of Michigan at Ann Arbor - Division of Radiation and Cancer Biology, Zhejiang University - Institute of Translational Medicine, Harvard Medical School - Department of Pathology and Zhejiang University - Institute of Translational Medicine
Downloads 7 (648,665)

Abstract:

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SAG, APC2, APC/C(CDH1), APC/C(CDC20), UBE2C, UBE2S, cell cycle, mitotic slippage, ubiquitylation.

4.

Discovery of Candesartan Cilexetic as a Novel Neddylation Inhibitor for Suppressing Tumor Growth

Number of pages: 57 Posted: 30 Sep 2019
Shanghai University of Traditional Chinese Medicine - Cancer Institute, East China University of Science and Technology (ECUST) - State Key Laboratory of Bioreactor Engineering, Zhejiang University - Institute of Translational Medicine, East China University of Science and Technology (ECUST) - State Key Laboratory of Bioreactor Engineering, Chinese Academy of Sciences (CAS) - CAS Center for Excellence in Molecular Cell Science, Shanghai University of Traditional Chinese Medicine - Cancer Institute, Shanghai University of Traditional Chinese Medicine - Cancer Institute, East China University of Science and Technology (ECUST) - State Key Laboratory of Bioreactor Engineering, Shanghai University of Traditional Chinese Medicine - Cancer Institute, East China University of Science and Technology (ECUST) - State Key Laboratory of Bioreactor Engineering, Shanghai Jiao Tong University (SJTU) - Shanghai Ninth People’s Hospital, Zhejiang University - Institute of Translational Medicine, East China University of Science and Technology (ECUST) - State Key Laboratory of Bioreactor Engineering and Shanghai Jiao Tong University (SJTU) - Department of Oncology
Downloads 4 (670,168)

Abstract:

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Neddylation, drug repurposing, candesartan cilexetic, NAE inhibitor