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Keren K. Griffiths

Columbia University Medical Center, Department of Anesthesiology

630 West 168th Street, 3rd Floor, Suite 3-470

New York, NY 10032

United States

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Scholarly Papers (1)

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Inefficient Thermogenic Mitochondrial Respiration Due to Futile Proton Leak in a Mouse Model of Fragile X Syndrome

Number of pages: 67 Posted: 20 Nov 2018
Keren K. Griffiths, Aili Wang, Lifei Wang, Matthew Tracey, Giulio Kleiner, Catarina M. Quinzii, Jose F. Perez-Zoghbi, Pawel Licznerski, Elizabeth A. Jonas and Richard J. Levy
Columbia University Medical Center, Department of Anesthesiology, Columbia University Medical Center, Department of Anesthesiology, Columbia University Medical Center, Department of Anesthesiology, Columbia University Medical Center, Department of Anesthesiology, Columbia University Medical Center, Department of Neurology, Columbia University Medical Center, Department of Neurology, Columbia University Medical Center, Department of Anesthesiology, Yale University - Section of Endocrinology, Yale University - Section of Endocrinology and Columbia University Medical Center, Department of Anesthesiology
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Abstract:

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Fragile X syndrome, Fmr1, mitochondria, proton leak, coenzyme Q, ubiquinone, permeability transition pore, thermogenic, uncoupled respiration, synaptogenesis