Cincinnati Children's Hospital Medical Center - Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center - Division of Reproductive Sciences, Vanderbilt University Medical Center, Department of Internal Medicine, Cincinnati Children's Hospital Medical Center - Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center - Division of Reproductive Sciences, Juntendo University School of Medicine – Department of Immunology, University of Tokyo - Department of Obstetrics and Gynecology and Cincinnati Children's Hospital Medical Center - Division of Reproductive Sciences