Mayo Clinic - Department of Cancer Biology, Johns Hopkins University - Department of Chemical and Biomolecular Engineering, Johns Hopkins University - Department of Chemical and Biomolecular Engineering, Mayo Clinic - Department of Biochemistry and Molecular Biology, Mayo Clinic - Department of Biochemistry and Molecular Biology, Mayo Clinic - Department of Cancer Biology, Mayo Clinic - Department of Cancer Biology, Mayo Clinic - Department of Cancer Biology, University of North Carolina (UNC) at Chapel Hill - Lineberger Comprehensive Cancer Center, Lerner Research Institute - Department of Cancer Biology, Lerner Research Institute - Department of Cancer Biology, Columbia University - Departments of Pathology and Cell Biology, Mayo Clinic - Department of Neurosurgery, Mayo Clinic - Department of Neurosurgery, Mayo Clinic - Florida - Brain Tumor Stem Cell Laboratory, National Institutes of Health (NIH) - 8Cell and Developmental Biology Center, Mayo Clinic - Department of Biochemistry and Molecular Biology, University of North Carolina (UNC) at Chapel Hill - Lineberger Comprehensive Cancer Center, Johns Hopkins University - Department of Chemical and Biomolecular Engineering, Columbia University - Department of Pathology and Cell Biology and Mayo Clinic - Department of Cancer Biology