Eicke Latz

German Center for Neurodegenerative Diseases (DZNE)

von Siebold Strasse 3a

Goettingen, 37075

Germany

University of Bonn - Institute of Innate Immunity

Bonn

Germany

University of Massachusetts Worcester - Department of Medicine

55 Lake Avenue North

Worcester, MA 01655

United States

SCHOLARLY PAPERS

4

DOWNLOADS

119

SSRN CITATIONS

0

CROSSREF CITATIONS

2

Scholarly Papers (4)

1.

PLCG2 Protective Variant p.P522R Modulates Tau Pathology and Disease Progression in Patients with Mild Cognitive Impairment

Number of pages: 83 Posted: 02 Jan 2019
University of Cologne - Division of Neurogenetics and Molecular Psychiatry, University of Lille II - RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, University of Bonn - Institute of Innate Immunity, VU University Amsterdam - Department of Neurology, Andalusian Bioinformatics Research Centre (CAEBi), University of Cologne - Division of Neurogenetics and Molecular Psychiatry, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Bonn - Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Paris-Saclay, University of Cologne - Division of Neurogenetics and Molecular Psychiatry, University of Erlangen-Nuremberg-Friedrich Alexander Universität Erlangen Nürnberg, University of Lausanne - Department of Psychiatry, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, VU University Amsterdam - Department of Neurology, VU University Amsterdam - Department of Neurology, University of Erlangen-Nuremberg-Friedrich Alexander Universität Erlangen Nürnberg, Charité - Universitätsmedizin Berlin - Department of Psychiatry and Psychotherapy, University of Montpellier, University of Bonn, Faculty of Medicine, Department of Psychiatry and Psychotherapy, Heidelberg University - Central Institute of Mental Health, University of Bordeaux - Bordeaux Population Health Research Center, University of Bordeaux - Victor Segalen Bordeaux 2 University, University of Freiburg - Department of Rehabilitation Psychiatry and Psychotherapy, Universitat Internacional de Catalunya, Carlos III Institute of Health, Carlos III Institute of Health, Universitat Internacional de Catalunya, Universitat Internacional de Catalunya, VU University Amsterdam - Amsterdam Public Health Research Institute, University of Amsterdam - Amsterdam Public Health Research Institute, VU University Amsterdam - Amsterdam Public Health Research Institute, VU University Amsterdam - Department of Neurology, University of Goettingen (Gottingen), Faculty of Medicine, University Medical Centre, Department of Psychiatry and Psychotherapy, University of Paris-Saclay, University of Goettingen (Gottingen), Faculty of Medicine, University Medical Centre, Department of Psychiatry and Psychotherapy, Universitat Internacional de Catalunya, German Center for Neurodegenerative Diseases (DZNE), University Medical Center Hamburg-Eppendorf, University of Leipzig - Institute for Social Medicine, Occupational Health and Public Health, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Lille II - RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, German Center for Neurodegenerative Diseases (DZNE), Carlos III Institute of Health, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, Andalusian Bioinformatics Research Centre (CAEBi), University of Bonn - Institute of Innate Immunity, University of Bonn, Faculty of Medicine, Department of Psychiatry and Psychotherapy, University of Lille II - RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, VU University Amsterdam - Department of Neurology, Andalusian Bioinformatics Research Centre (CAEBi), German Center for Neurodegenerative Diseases (DZNE), Universitat Internacional de Catalunya and University of Cologne - Division of Neurogenetics and Molecular Psychiatry
Downloads 68 (347,534)

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2.

Platelets Fuel the Inflammasome Activation of Innate Immune Cells

CELL-REPORTS-D-19-03149
Number of pages: 72 Posted: 21 Aug 2019
University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, Instituto René Rachou - Laboratório de Malária, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, Fundação Oswaldo Cruz - Laboratório de Malária, Universidade Federal de Mato Grosso - Departamento de Clínica Médica, Cedars Sinai Medical Center - Departments of Pediatrics and Biomedical Sciences, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn - Institute of Innate Immunity
Downloads 29 (490,609)

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Inflammasomes, interleukin-1, auto-inflammatory diseases, platelets, malaria, NLRP3

3.

Proteopathic Tau Primes and Activates Interleukin-1ß(Il-1ß) via MyD88- and NLRP3-ASC-Inflammasome Dependent Pathways

NEURON-D-19-00624
Number of pages: 59 Posted: 02 May 2019
University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Molecular Genetics and Microbiology, University of New Mexico - Department of Neurosciences, University of New Mexico - Department of Neurosciences, University of New Mexico, School of Medicine, Department of Cell Biology and Physiology, Northwestern University, Feinberg School of Medicine, Cognitive Neurology & Alzheimer’s Disease Center (CNADC), Northwestern University, Feinberg School of Medicine, Cognitive Neurology & Alzheimer’s Disease Center (CNADC), University of New Mexico - Department of Neurosciences, University of New Mexico - Department of Neurosciences, German Center for Neurodegenerative Diseases (DZNE), University of Bonn - Institute of Innate Immunity and University of New Mexico - Department of Molecular Genetics and Microbiology
Downloads 12 (592,466)
Citation 1

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Tauopathies, tau, MAPT, IL-1β, neuroinflammation, microglia, inflammasomes, NLRP3, ASC, MyD88

4.

Amyloid β Clustering Around ASC Fibrils Boost Its Toxicity in Microglia

CELL-REPORTS-D-19-04107
Number of pages: 36 Posted: 21 Oct 2019
University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry, University of Bonn - Institute of Structural Biology, University of Bonn - Institute of Structural Biology, Max Planck Institute for Biophysical Chemistry - Department of Structural Dynamics, German Center for Neurodegenerative Diseases (DZNE), University of Bonn - Institute of Structural Biology and University of Bonn - Department of Neurodegenerative Disease and Gerontopsychiatry
Downloads 10 (605,574)

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ASC, Aβ, microglia, NLRP3 inflammasome, Alzheimer's disease