Carla Mattos

Northeastern University - Department of Chemistry and Chemical Biology

Boston, MA 02115

United States

SCHOLARLY PAPERS

2

DOWNLOADS

21

SSRN CITATIONS

0

CROSSREF CITATIONS

0

Scholarly Papers (2)

1.

Isoform-Specific Destabilization of the Active Site Reveals Molecular Mechanism of Intrinsic Activation of KRas G13D

Number of pages: 66 Posted: 26 Feb 2019
Northeastern University - Department of Chemistry and Chemical Biology, Harvard University - Beth Israel Deaconess Medical Center, Northeastern University - Department of Chemistry and Chemical Biology, Northeastern University - Department of Chemistry and Chemical Biology, Van Andel Research Institute, Van Andel Research Institute, Northeastern University - Center for Drug Discovery, Van Andel Research Institute, Harvard University - Cancer Research Institute and Northeastern University - Department of Chemistry and Chemical Biology
Downloads 15 (571,972)

Abstract:

Loading...

Ras GTPases, KRas G13D structures, conformational states, nucleotide exchange mutant, activation cycle, KRas G13D mouse model, colorectal cancer, oncogene

2.

The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin

STRUCTURE-D-19-00185
Number of pages: 59 Posted: 11 Jul 2019
National Laboratory for Cancer Research, University of Illinois at Chicago, Northeastern University, Northeastern University, Northeastern University - Department of Chemistry and Chemical Biology, University of Illinois at Chicago and National Institutes of Health (NIH) - National Cancer Institute at Frederick
Downloads 6 (631,482)

Abstract:

Loading...

post-translational modifications, farnesylation and methylation, phosphatidylinositol, PIP2, NMR, MD simulation, SAXS, PI3K