Philip L. De Jager

Columbia University - Center for Translational and Systems Neuroimmunology

630 West 168th Street, 3rd Floor, Suite 3-470

New York, NY 10032

United States

SCHOLARLY PAPERS

4

DOWNLOADS

109

SSRN CITATIONS

3

CROSSREF CITATIONS

0

Scholarly Papers (4)

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1.

Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology

Number of pages: 64 Posted: 12 Nov 2019
Hyun-Sik Yang, Charles C. White, Hans-Ulrich Klein, Lei Yu, Christopher Gaiteri, Yiyi Ma, Daniel Felsky, Sara Mostafavi, Vladislav Petyuk, Reisa A. Sperling, Nilüfer Ertekin-Taner, Julie Schneider, David A. Bennett and Philip L. De Jager
Harvard University - Brigham and Women's Hospital, Massachusetts Institute of Technology and Harvard University - Broad Institute, Columbia University - Center for Translational & Computational Neuroimmunology, Rush University - Alzheimer’s Disease Center, Rush University - Alzheimer’s Disease Center, Massachusetts Institute of Technology and Harvard University - Broad Institute, Krembil Centre for Neuroinformatics - Centre for Addiction and Mental Health, University of British Columbia (UBC) - Department of Medical Genetics, Pacific Northwest National Laboratory, Massachusetts General Hospital - Department of Neurology, Mayo Clinic - Florida - Department of Neuroscience, Rush University - Alzheimer’s Disease Center, Rush University Medical Center - Rush Alzheimer’s Disease Center and Columbia University - Center for Translational and Systems Neuroimmunology
Downloads 34 (705,424)

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Expression quantitative trait loci (eQTL), Genetics, Gene expression, Gene regulation, transcription, Biochemical networks, gene co-expression networks, RNA, micro RNA, Functional genomics, Genome-wide association study (GWAS), Genetic interaction, Epistasis, neurodegeneration, Aging, Dementia, Cognition, Cognitive aging, Cognitive Resilience, Neuropathology, Amyloid-beta, Alzheimer's disease, TDP-43, Limbic-predominant age-related TDP-43 encephalopathy (LATE), APOE, TMEM106B, GRN, RBFOX1, RNA splicing, Synapse, Lysosome, Myelination

2.

Human Herpesvirus-6 (HHV-6) Detection in Alzheimer's Disease Cases and Controls Across Multiple Cohorts

Number of pages: 35 Posted: 07 Oct 2019
Mary Alice Allnutt, Kory Johnson, David A. Bennett, Sarah M. Connor, Juan C. Troncoso, Olga Pletnikova, Marilyn S. Albert, Susan M. Resnick, Sonja W. Scholz, Philip L. De Jager and Steven Jacobson
National Institutes of Health - Viral Immunology Section, National Institutes of Health - Bioinformatics Section, Rush University Medical Center - Rush Alzheimer’s Disease Center, Columbia University Medical Center - Center for Translational & Computational Neuroimmunology, Johns Hopkins University - Department of Pathology, Johns Hopkins University - School of Medicine, Johns Hopkins University - Department of Neurology, National Institutes of Health - Laboratory of Behavioral Neuroscience, National Institutes of Health - Neurodegenerative Diseases Research Unit, Columbia University - Center for Translational and Systems Neuroimmunology and National Institutes of Health (NIH) - Viral Immunology Section
Downloads 34 (705,424)
Citation 1

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Herpesvirus, Alzheimer's disease, Human herpesvirus-6

3.

Cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Susceptibility Gene, is Required for Synaptic Transmission and Proteostasis

Number of pages: 75 Posted: 10 Jan 2019
Shamsideen A. Ojelade, Tom V. Lee, Nikolaos Giagtzoglou, Lei Yu, Berrak Ugur, Lita Duraine, Zhongyuan Zuo, Vladislav Petyuk, Philip L. De Jager, David A. Bennett, Benjamin R. Arenkiel, Hugo J. Bellen and Joshua M. Shulman
Baylor University, College of Medicine, Department of Neurology, Baylor University, College of Medicine, Department of Neurology, Baylor University, College of Medicine, Department of Neurology, Rush University Medical Center - Rush Alzheimer’s Disease Center, Baylor University - Program in Developmental Biology, Baylor College of Medicine - Howard Hughes Medical Institute, Baylor College of Medicine - Department of Molecular and Human Genetics, Pacific Northwest National Laboratory, Columbia University - Center for Translational and Systems Neuroimmunology, Rush University Medical Center - Rush Alzheimer’s Disease Center, Baylor University, College of Medicine, Howard Hughes Medical Institute, Texas Children’s Hospital - Jan and Dan Duncan Neurologic Research Institute and Baylor University, College of Medicine, Department of Neurology
Downloads 21 (802,861)
Citation 1

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calcium; PMCA; Synapsin; ubiquitin-proteasome system; Alzheimer’s Disease; 14-3-3; GWAS; neurofibrillary tangles; Tau; endocytosis; exocytosis; neuromuscular junction

4.

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA-Splicing and Neurodegeneration in Alzheimer's Disease

Number of pages: 82 Posted: 14 Feb 2019
Yi-Chen Hsieh, Caiwei Guo, Hari K. Yalamanchili, Measho Abreha, Rami Al-Ouran, Yarong Li, Eric B. Dammer, James J. Lah, Allan I. Levey, David A. Bennett, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu and Joshua M. Shulman
Baylor College of Medicine - Department of Molecular and Human Genetics, Baylor University - Department of Neuroscience, Baylor University - Department of Pediatrics, Emory University - Department of Biochemistry, Baylor University - Department of Pediatrics, Baylor University, College of Medicine, Department of Neurology, Emory University - Department of Biochemistry, Emory University - Department of Neurology, Emory University - Department of Neurology, Rush University Medical Center - Rush Alzheimer’s Disease Center, Columbia University - Center for Translational and Systems Neuroimmunology, Emory University - Winship Cancer Institute, Baylor University - Department of Pediatrics and Baylor University, College of Medicine, Department of Neurology
Downloads 20 (811,288)
Citation 2

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Alzheimer’s disease, neurodegeneration, Tau, neurofibrillary tangles, spliceosome, RNA splicing, cryptic splicing, intron retention, SmB, U1-70K