Wei Wei

Institute for Systems Biology

401 Terry Ave N.

Seattle, WA 98109

United States

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Scholarly Papers (1)

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Kinetic Inference Resolves Epigenetic Mechanism of Drug Resistance in Melanoma

CANCER-CELL-D-19-00753
Number of pages: 75 Posted: 21 Aug 2019
California Institute of Technology - Division of Chemistry and Chemical Engineering, University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), California Institute of Technology - Division of Biology and Biological Engineering, Institute for Systems Biology, Peking University - Key Laboratory of Carcinogenesis and Translational Research, California Institute of Technology - Division of Chemistry and Chemical Engineering, California Institute of Technology - Division of Chemistry and Chemical Engineering, California Institute of Technology - Division of Biology and Biological Engineering, University of California, Los Angeles (UCLA) - Department of Medicine, City of Hope - Department of Molecular and Cellular Biology, California Institute of Technology - Division of Chemistry and Chemical Engineering, Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), Institute for Systems Biology, Institute for Systems Biology, Institute for Systems Biology, California Institute of Technology - Division of Chemistry and Chemical Engineering, California Institute of Technology - Division of Chemistry and Chemical Engineering, University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), Fudan University - Shanghai Cancer Center (FUSCC), City of Hope - Department of Molecular and Cellular Biology, City of Hope - Department of Molecular and Cellular Biology, Institute for Systems Biology, Shanghai Jiao Tong University (SJTU) - MOE Key Laboratory of Systems Biomedicine (KLSB), University of California, Los Angeles (UCLA) - Department of Molecular and Medical Pharmacology (DMMP), University of California, Los Angeles (UCLA) - Department of Medicine, California Institute of Technology - Division of Biology and Biological Engineering, Peking University - Key Laboratory of Carcinogenesis and Translational Research, California Institute of Technology - Division of Chemistry and Chemical Engineering and Institute for Systems Biology
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Abstract:

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non-genetic drug resistance, epigenetic plasticity, chromatin remodeling, melanoma, targeted therapy resistance, multi-omics characterization, systems biology, information theory, dynamic systems, histone modification