Children’s Hospital of Philadelphia - Division of Oncology, Children’s Hospital of Philadelphia - Division of Oncology, Children’s Hospital of Philadelphia - Department of Biomedical and Health Informatics, University of Tuebingen, Children’s Hospital of Philadelphia - Department of Biomedical and Health Informatics, University of Pennsylvania - Perelman School of Medicine, Children’s Hospital of Philadelphia - Department of Pathology and Lab Medicine, University of Pennsylvania - Perelman School of Medicine, University of Tuebingen and Children’s Hospital of Philadelphia - Division of Oncology