University of Bonn - Myeloid Cell Biology, Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Department of Internal Medicine, University of Melbourne - Department of Paediatrics, Radboud University Nijmegen - Department of Hematology, Radboud University Nijmegen - Department of Hematology, Radboud University Medical Center - Department of Internal Medicine and Radboud Center for Infectious Diseases, German Center for Neurodegenerative Diseases (DZNE) - Single Cell Genomics and Epigenomics Unit, German Center for Neurodegenerative Diseases (DZNE) - Single Cell Genomics and Epigenomics Unit, University of Bonn, Life and Medical Sciences Institute (LIMES), Genomics & Immunoregulation, University of Bonn, Life and Medical Sciences Institute (LIMES), Genomics & Immunoregulation, Radboud University Nijmegen - Department of Internal Medicine, University of Groningen - Department of Human Genetics, Statens Serums Institut - Research Center for Vitamins and Vaccines, University of Bonn - Life and Medical Sciences Institute (LIMES), Radboud University Nijmegen - Department of Internal Medicine, University of Melbourne - Department of Paediatrics, Radboud University Nijmegen - Department of Internal Medicine and University of Bonn - Department of Quantitative Systems Biology