Mariana L. de Souza

University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry

Sao Paulo

Brazil

  • University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry

SCHOLARLY PAPERS

2

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68

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1

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Scholarly Papers (2)

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1.

Structure-Activity Relationships of Novel N-Imidazoylpiperazines with Potent Anti-Trypanosoma Cruzi Activity

Number of pages: 35 Posted: 09 Jun 2023
Luiz Dias, Rocio Marisol Espinoza Chávez, Celso de Oliveira Rezende Junior, Mariana L. de Souza, Ivani Pauli, Marilia Valli, Leonardo Ferreira, Rafael Consolin Chelucci, Simone Michelan-Duarte, Renata Krogh, Fernando Bezerra Romualdo da Silva, Fabio Cardoso Cruz, Aldo Sena de Oliveira and Adriano D. Andricopulo
Universidade Estadual de Campinas (UNICAMP), Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo, University of Sao Paulo, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo, University of Sao Paulo, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, Federal University of São Paulo (UNIFESP), Federal University of São Paulo (UNIFESP), Federal University of Santa Catarina (UFSC) and University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry
Downloads 55 (675,336)

Abstract:

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Trypanosoma cruzi, Chagas disease, N-imidazoylpiperazines, SAR, Hit-to-Lead, drug discovery

2.

Carbamoyl Imidazoles As Potent, Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo Trypanocidal Activity: A Structure-Based Drug Design Approach

Number of pages: 115 Posted: 17 May 2019
Mariana L. de Souza, Celso de Oliveira Rezende Junior, Rafaela S. Ferreira, Rocio Marisol Espinoza Chávez, Leonardo Ferreira, Brian W. Slafer, Luma G. Magalhães, Renata Krogh, Glaucius Oliva, Fabio Cardoso Cruz, Luiz Carlos Dias and Adriano D. Andricopulo
University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, Federal University of Minas Gerais (UFMG) - Department of Biochemistry and Immunology, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, Federal University of São Paulo (UNIFESP) - Department of Pharmacology, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry and University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry
Downloads 13 (1,011,052)

Abstract:

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Chagas disease, virtual screening, organic synthesis, structure-activity relationships, drug design, drug discovery, SBDD, neglected tropical diseases